[email protected]   Old Website Link
Login to Email
        [email protected]   Old Website Link
Login to Email

Dr. A. Das

Associate Professor, Department of Pharmaceutical Sciences
  • Email - [email protected]
  • Department of Pharmaceutical Sciences
  • Designation - Associate Professor

Profile

Education:

  1. Bachelor’s Degree : B.Pharm (Dibrugarh University)
  2. Master’s Degree : M.Pharm (Birla Institute of Technology, Mesra, Ranchi)
  3. Ph.D.: Pharmaceutical Sciences (Dibrugarh University)
  4. Other: PDCR (Catalyst Clinical Services, New Delhi), Post Doc (USF-Health)

Professional Experience:

  • 18 Years in Teaching & Research

Areas of Interest/ Specialization:

  • Medicinal Chemistry/ Drug Discovery and Development

Research Projects:

Projects Completed as PI:

  1. AICTE funded RPS Project entitled “Phytochemical and Pharmacological Screening of the fruits of Garcinia cowa with special reference to Antidiarrhoeal activity”.

Projects Completed as Co-PI:

  1. Synthesis of hybrid class phenylthiazole 1,3,5-triazine derivatives as novel antimalarial for Pf-DHFR-TS inhibition.(DBT Funded)

Ph.D Scholars:

Sl. No.

Name

Topic

Status

(On-going /Completed)

1

Ms Kalyani Pathak

Isolation and Characterization of Bioactive molecule(s)of the Leaves of Annona reticulate Linn., a folklore herbal drug of Assam

On-going

2

R Vanlalruata

In-Silico studies, Synthesis and Evaluation of Anti-cancer activity of Novel Hybrid Xanthone Derivatives

On-going

3

Manash Pratim Pathak

Pharmacological Intervention of obesity induced airway hyperresponsiveness using murine model.

On-going

4

Shyamalendu Nath

Mining of biologically active molecules from some plants belonging to the genus Caesalpinia and Elsholtzia from Jorhat and Dibrugarh districts of Assam

On-going

5

Ejiofor Innocentmary Ifedibaluchukwii

Phytochemical and Pharmacological Investigation of Vernonia amygdalin- A Traditional Medicinal Plant of Nigeria

On-going

 

Patents:

Patent Applications filed:

  1. Aparoop Das & Dipak ChetiaPatent
    Application No.: 1324/KOL/2013.
    Date of filing: 25/11/2013.
    Title: Method for obtaining novel Xanthone compounds

 

Extension Service:

  1. Associated with various Professional bodies

 

 

Publications

  1. A. Kaushik, J.J. Kaushik, A. Das & V.Saini., Antimycotic effects of essential oil ofleaves of Artemesia nilagirica Linn., Indian Perfumer, 49(4), Oct-Dec. 2005, 515-517.
  2. Nida Akhtar, Mohd. Ali & Aparoop Das, Antibacterial Activity of Inula cuspidate leaves., Indian journal Nat. Prod., 22 (3), 2006, 33-34.
  3. Aparoop Das, Atul Kaushik, Jeevan Jyoti & Veerma Ram, Anti-inflammatory activities of Cleome isocandra seed oil in experimental animal models., Universities Journal of Phyto-chemistry and Ayuevedic Heights, 2 (1), April 2006, 11-13.
  4. P. Gahtori, A. Das and H. Bhatt., Synthesis and antibacterial assessment of N-[4-(4-substituted phenyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-amine, Indian Journal of Pharmaceutical Sciences., 71(1): 79-82, 2009. 
  5. Udaya Pratap Singh, Aparoop Das, Dipak Chetia, Ashokanshu Bhattacharya, Yadav Pankajkumar Subhaschandra, Vikash Kumar & Hans Raj Bhatt., Synthesis and Antibacterial Activity of Some 2,4,6-trisubstituted-1,3,5-triazines., Lat Am J Pharm., 29(4):607-11, 2010.
  6. P. Gahtori, A. Singh, S.K. Ghosh, A. Das and U. Archana, Synthesis of some  substituted Phenythiazolyl 1,3,5-Triazine derivatives., Asian Journal of Chemistry., 23(3): 1189-1192, 2011.
  7. A Kaushik, J J Kaushik, A Das, S Gemal and D Gaim., Preliminary studies on anti-inflammatory activities of Diplazium esculentum in experimental animal models., International Journal of Pharmaceutical Sciences and Research., 2(5), 1251-53, April, 2011.
  8. P. Gahtori, A. Das and R.Mishra, Design, Synthesis and Antibacterial Activity of Substituted PhenylThiazolyl s-Triazines.,  Pharmaceutical Chemistry Journal., 45(4), 248-52, July, 2011.
  9. Ravi Bhushan singh, Nirupam Das, Srabanti Jana and Aparoop Das, Synthesis and In Vitro Antibacterial Screening of some New 2,4,6 Trisubstituted-1,3,5- Triazine  Derivatives., Letters in Drug Design & Discovery., 9, 316-321. 2012,
  10. S. Jana and A. Das., Synthesis and Assessment of Antibacterial Activity of some Novel 4-Benzyl-piperazinyl-s-triazine  Derivatives., Asian Journal of Chemistry., 25(1), 186-90, 2013.
  11. Pratap Parida, R.N.S. Yadav, Brajesh Shankar, Dipankar Chakraborty, A. Das, Nisha Kumari Singh., In-silico protein ligand interaction study of typical antipsychotic drugs against dopaminergic D2 receptor., International journal of Pharmacy and Pharmaceutical Sciences., 5(2): 183-189, 2013.
  12. Aparoop Das, Pratap Parida, Neha agarwal, Jaya Shree, Brajesh Shankar and dipankar Chakraborty., Molecular docking study of 3,6bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) xanthone derivatives as PGHS- 2 inhibitors., Journal of Applied Pharmaceutical Science., Vol.3 (4 Suppl 1), pp.S13-S22, May, 2013.
  13. Lakhyajit Boruah, Aparoop Das, lalit mohan Nainwal, Neha Agarwal, Brajesh Shankar., In-Silico Drug Design: A revolutionary approach to change the concept of current Drug Discovery Process., Indian Journal of Pharmaceutical & Biological Research.., Vol.1(1), 60-73, June., 2013.
  14. A Das, K Debnath, P S Bairy and L Nainwal., Synthesis and antimicrobial screening of a series of  3,6bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) xanthone derivatives., Current Trends in Pharmaceutical Research., 2(1), 13-23, 2013.
  15. Aparoop Das, Md. Mutahar Shaikh and Srabanti Jana., Design, synthesis and in vitro  antibacterial screening of some novel 3-pentyloxy-1-hydroxyxanthone Derivatives., Medicinal Chemistry Research., 23, 436-444, 2014.
  16. Pratap Parida, Samhita Kalita, Brajesh Shankar, RNS Yadav and Aparoop Das., Homology modelling and docking studies of Plasmodium falciparum telomerase reverse transcriptase with berberine and some of its derivatives., Bangladesh J Pharmacol., 9, 96-104, 2014.
  17. Lalit Mohan Nainwal, Pratap Parida, Aparoop Das and ParthasarathiBairy., Design and docking of novel series of hybrid xanthones as anti-cancer agent to target human DNA topoisomerase 2-alpha., Bangladesh J Pharmacol., 9, 208-217, 2014.
  18. Brajesh Shankar, Aparoop Das and Pratap Parida., Design, Molecular Docking Study and Synthesis of 3,6-bis(3′-substituted propoxy)xanthone Derivatives as COX-2 Inhibitors., Asian Journal of Chemistry., 27(12), 4634-4640,2015.
  19. Partha Sarathi Bairy, Brajesh Shankar, Aparoop Das., Diabetes mellitus and antidiabetics with reference to Alpha Glucosidase Inhibitors., Journal of Biomedical and Pharmaceutical Research., 4(6), 10-16,2015.
  20. Partha Sarathi Bairy, Aparoop Das, Lalit Mohan Nainwal, Tapan Kumar Mahanta, Mukesh Kumar Kumawat, Pradyumna Kishore Mohapatra and Pratap Parida., Design, synthesis and anti-diabetic activity of some novel xanthone derivatives targetinf α-glucosidase., Bangladesh J Pharmacol., 11:308-318. 2016.
  21. Aparoop Das, Madhusmrita Dutta and Mami Malakar., In-silico study, synthesis and biological evaluation of some substituted xanthone derivatives as alpha-glucosidase inhibitor., World Journal of Pharmaceutical Sciences., ISSN (Print): 2321-3310; ISSN (Online): 2321-3086., 2016.
  22. Aparoop Das, Urvashee Gogoi, Junmoni Kalita and Satyasish Sandilya., Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel COX-2 Inhibitors Targeting Prostaglandin Endoperoxide Synthase -2., Current Enzyme Inhibition., 12(2), 195-204., 2016.
  23. Prashant Gahtori. Rahul Pandey, Vinod Kumar, Surajit Kumar Ghosh, Aparoop Das, Jun Moni Kalita, Supriya Sahu, Anil Prakash, Divya Ranjan Bhattacharyya., Toward resistance‐compromised DHFR inhibitors part 1:Combined structure/ligand‐based virtual screenings and ADME-Tox profiling.,m Journal of Chemometrics., 1-20, 2016.
  24. Partha Sarathi Bairy, Nilutpal Sharma Bora, Bibhuti Bhusan Kakoti, Aparoop Das, Lalit Mohan Nainwal, Barnali Gogoi., Preliminary phytochemical screening, in-vitro antioxidant activity, total polyphenolic and flavonoid content of Garcinia lanceifolia Roxb. and Citrus maxima (Burm.) Merr.., J App Pharm Sci. 6(9): 133-139; 2016.
  25. Hans Raj Bhatt, Udaya Pratap Singh, Pankaj S. Yadav, Vikas Kumar, Prashant Gahtori, Aparoop Das, Dipak Chetia, Anil Prakash, J. Mahanta., Synthesis, characterization and antimalarial activity of hybrid 4-aminoquinoline-1,3,5-triazine  Derivatives., Arabian Journal of Chemistry., 9: S625-S631; 2016.
Profile

Profile

Education:

  1. Bachelor’s Degree : B.Pharm (Dibrugarh University)
  2. Master’s Degree : M.Pharm (Birla Institute of Technology, Mesra, Ranchi)
  3. Ph.D.: Pharmaceutical Sciences (Dibrugarh University)
  4. Other: PDCR (Catalyst Clinical Services, New Delhi), Post Doc (USF-Health)

Professional Experience:

  • 18 Years in Teaching & Research

Areas of Interest/ Specialization:

  • Medicinal Chemistry/ Drug Discovery and Development

Research Projects:

Projects Completed as PI:

  1. AICTE funded RPS Project entitled “Phytochemical and Pharmacological Screening of the fruits of Garcinia cowa with special reference to Antidiarrhoeal activity”.

Projects Completed as Co-PI:

  1. Synthesis of hybrid class phenylthiazole 1,3,5-triazine derivatives as novel antimalarial for Pf-DHFR-TS inhibition.(DBT Funded)

Ph.D Scholars:

Sl. No.

Name

Topic

Status

(On-going /Completed)

1

Ms Kalyani Pathak

Isolation and Characterization of Bioactive molecule(s)of the Leaves of Annona reticulate Linn., a folklore herbal drug of Assam

On-going

2

R Vanlalruata

In-Silico studies, Synthesis and Evaluation of Anti-cancer activity of Novel Hybrid Xanthone Derivatives

On-going

3

Manash Pratim Pathak

Pharmacological Intervention of obesity induced airway hyperresponsiveness using murine model.

On-going

4

Shyamalendu Nath

Mining of biologically active molecules from some plants belonging to the genus Caesalpinia and Elsholtzia from Jorhat and Dibrugarh districts of Assam

On-going

5

Ejiofor Innocentmary Ifedibaluchukwii

Phytochemical and Pharmacological Investigation of Vernonia amygdalin- A Traditional Medicinal Plant of Nigeria

On-going

 

Patents:

Patent Applications filed:

  1. Aparoop Das & Dipak ChetiaPatent
    Application No.: 1324/KOL/2013.
    Date of filing: 25/11/2013.
    Title: Method for obtaining novel Xanthone compounds

 

Extension Service:

  1. Associated with various Professional bodies

 

 

Publications

Publications

 

  1. A. Kaushik, J.J. Kaushik, A. Das & V.Saini., Antimycotic effects of essential oil ofleaves of Artemesia nilagirica Linn., Indian Perfumer, 49(4), Oct-Dec. 2005, 515-517.
  2. Nida Akhtar, Mohd. Ali & Aparoop Das, Antibacterial Activity of Inula cuspidate leaves., Indian journal Nat. Prod., 22 (3), 2006, 33-34.
  3. Aparoop Das, Atul Kaushik, Jeevan Jyoti & Veerma Ram, Anti-inflammatory activities of Cleome isocandra seed oil in experimental animal models., Universities Journal of Phyto-chemistry and Ayuevedic Heights, 2 (1), April 2006, 11-13.
  4. P. Gahtori, A. Das and H. Bhatt., Synthesis and antibacterial assessment of N-[4-(4-substituted phenyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-amine, Indian Journal of Pharmaceutical Sciences., 71(1): 79-82, 2009. 
  5. Udaya Pratap Singh, Aparoop Das, Dipak Chetia, Ashokanshu Bhattacharya, Yadav Pankajkumar Subhaschandra, Vikash Kumar & Hans Raj Bhatt., Synthesis and Antibacterial Activity of Some 2,4,6-trisubstituted-1,3,5-triazines., Lat Am J Pharm., 29(4):607-11, 2010.
  6. P. Gahtori, A. Singh, S.K. Ghosh, A. Das and U. Archana, Synthesis of some  substituted Phenythiazolyl 1,3,5-Triazine derivatives., Asian Journal of Chemistry., 23(3): 1189-1192, 2011.
  7. A Kaushik, J J Kaushik, A Das, S Gemal and D Gaim., Preliminary studies on anti-inflammatory activities of Diplazium esculentum in experimental animal models., International Journal of Pharmaceutical Sciences and Research., 2(5), 1251-53, April, 2011.
  8. P. Gahtori, A. Das and R.Mishra, Design, Synthesis and Antibacterial Activity of Substituted PhenylThiazolyl s-Triazines.,  Pharmaceutical Chemistry Journal., 45(4), 248-52, July, 2011.
  9. Ravi Bhushan singh, Nirupam Das, Srabanti Jana and Aparoop Das, Synthesis and In Vitro Antibacterial Screening of some New 2,4,6 Trisubstituted-1,3,5- Triazine  Derivatives., Letters in Drug Design & Discovery., 9, 316-321. 2012,
  10. S. Jana and A. Das., Synthesis and Assessment of Antibacterial Activity of some Novel 4-Benzyl-piperazinyl-s-triazine  Derivatives., Asian Journal of Chemistry., 25(1), 186-90, 2013.
  11. Pratap Parida, R.N.S. Yadav, Brajesh Shankar, Dipankar Chakraborty, A. Das, Nisha Kumari Singh., In-silico protein ligand interaction study of typical antipsychotic drugs against dopaminergic D2 receptor., International journal of Pharmacy and Pharmaceutical Sciences., 5(2): 183-189, 2013.
  12. Aparoop Das, Pratap Parida, Neha agarwal, Jaya Shree, Brajesh Shankar and dipankar Chakraborty., Molecular docking study of 3,6bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) xanthone derivatives as PGHS- 2 inhibitors., Journal of Applied Pharmaceutical Science., Vol.3 (4 Suppl 1), pp.S13-S22, May, 2013.
  13. Lakhyajit Boruah, Aparoop Das, lalit mohan Nainwal, Neha Agarwal, Brajesh Shankar., In-Silico Drug Design: A revolutionary approach to change the concept of current Drug Discovery Process., Indian Journal of Pharmaceutical & Biological Research.., Vol.1(1), 60-73, June., 2013.
  14. A Das, K Debnath, P S Bairy and L Nainwal., Synthesis and antimicrobial screening of a series of  3,6bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) xanthone derivatives., Current Trends in Pharmaceutical Research., 2(1), 13-23, 2013.
  15. Aparoop Das, Md. Mutahar Shaikh and Srabanti Jana., Design, synthesis and in vitro  antibacterial screening of some novel 3-pentyloxy-1-hydroxyxanthone Derivatives., Medicinal Chemistry Research., 23, 436-444, 2014.
  16. Pratap Parida, Samhita Kalita, Brajesh Shankar, RNS Yadav and Aparoop Das., Homology modelling and docking studies of Plasmodium falciparum telomerase reverse transcriptase with berberine and some of its derivatives., Bangladesh J Pharmacol., 9, 96-104, 2014.
  17. Lalit Mohan Nainwal, Pratap Parida, Aparoop Das and ParthasarathiBairy., Design and docking of novel series of hybrid xanthones as anti-cancer agent to target human DNA topoisomerase 2-alpha., Bangladesh J Pharmacol., 9, 208-217, 2014.
  18. Brajesh Shankar, Aparoop Das and Pratap Parida., Design, Molecular Docking Study and Synthesis of 3,6-bis(3′-substituted propoxy)xanthone Derivatives as COX-2 Inhibitors., Asian Journal of Chemistry., 27(12), 4634-4640,2015.
  19. Partha Sarathi Bairy, Brajesh Shankar, Aparoop Das., Diabetes mellitus and antidiabetics with reference to Alpha Glucosidase Inhibitors., Journal of Biomedical and Pharmaceutical Research., 4(6), 10-16,2015.
  20. Partha Sarathi Bairy, Aparoop Das, Lalit Mohan Nainwal, Tapan Kumar Mahanta, Mukesh Kumar Kumawat, Pradyumna Kishore Mohapatra and Pratap Parida., Design, synthesis and anti-diabetic activity of some novel xanthone derivatives targetinf α-glucosidase., Bangladesh J Pharmacol., 11:308-318. 2016.
  21. Aparoop Das, Madhusmrita Dutta and Mami Malakar., In-silico study, synthesis and biological evaluation of some substituted xanthone derivatives as alpha-glucosidase inhibitor., World Journal of Pharmaceutical Sciences., ISSN (Print): 2321-3310; ISSN (Online): 2321-3086., 2016.
  22. Aparoop Das, Urvashee Gogoi, Junmoni Kalita and Satyasish Sandilya., Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel COX-2 Inhibitors Targeting Prostaglandin Endoperoxide Synthase -2., Current Enzyme Inhibition., 12(2), 195-204., 2016.
  23. Prashant Gahtori. Rahul Pandey, Vinod Kumar, Surajit Kumar Ghosh, Aparoop Das, Jun Moni Kalita, Supriya Sahu, Anil Prakash, Divya Ranjan Bhattacharyya., Toward resistance‐compromised DHFR inhibitors part 1:Combined structure/ligand‐based virtual screenings and ADME-Tox profiling.,m Journal of Chemometrics., 1-20, 2016.
  24. Partha Sarathi Bairy, Nilutpal Sharma Bora, Bibhuti Bhusan Kakoti, Aparoop Das, Lalit Mohan Nainwal, Barnali Gogoi., Preliminary phytochemical screening, in-vitro antioxidant activity, total polyphenolic and flavonoid content of Garcinia lanceifolia Roxb. and Citrus maxima (Burm.) Merr.., J App Pharm Sci. 6(9): 133-139; 2016.
  25. Hans Raj Bhatt, Udaya Pratap Singh, Pankaj S. Yadav, Vikas Kumar, Prashant Gahtori, Aparoop Das, Dipak Chetia, Anil Prakash, J. Mahanta., Synthesis, characterization and antimalarial activity of hybrid 4-aminoquinoline-1,3,5-triazine  Derivatives., Arabian Journal of Chemistry., 9: S625-S631; 2016.
Courses Taken
Current Courses
Sponsored Projects