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Dr. A. Das

Professor, Department of Pharmaceutical Sciences
  • Email - aparoopdas@dibru.ac.in
  • Department of Pharmaceutical Sciences
  • Designation - Professor

Profile

Education:

  1. Bachelor’s Degree : B.Pharm (Dibrugarh University)
  2. Master’s Degree : M.Pharm (Birla Institute of Technology, Mesra, Ranchi)
  3. Ph.D.: Pharmaceutical Sciences (Dibrugarh University)
  4. Other: PDCR (Catalyst Clinical Services, New Delhi), Post Doc (USF-Health)

Professional Experience:

  • 25 Years in Teaching & Research

Areas of Interest/ Specialization:

  • Medicinal Chemistry/ Drug Discovery and Development

RESEARCH PROJECTS:

Projects Completed as PI:

  1. AICTE funded RPS Project entitled “Phytochemical and Pharmacological Screening of the fruits of Garcinia cowa with special reference to Antidiarrhoeal activity”. (PI)
  2. AICTE funded RPS-NER Project entitled “Design, synthesis and characterization of topoisomerase II alpha xanthone inhibitors and their chemotherapeutic polymeric nano carriers for the treatment of colorectal cancer”. (PI)

Research Project Completed as Co-PI: DBT Funded:

  1. Synthesis of hybrid class phenylthiazole 1, 3, 5-triazine derivatives as novel antimalarial for Pf-DHFR-TS inhibition.

Research Project Completed as Mentor:

  1. ICMR RA Project entitled “Isolation and characterization of the active principles of leaves of Annona reticulate And their encapsulation into polymeric nanostructured drug delivery system for the treatment of Diabetes”F.No. 45/10/2018/TM/BMS (Mentor)
  2. Design, Synthesis and Evaluation of hybrid xanthone derivatives as potential anti-cancer agents. (UGC National Fellowship) F.No.61-1/2019 (SA-III)(Mentor)

Research Project Ongoing as Mentor:

  1. DHR-Women Scientist A project titled “Fabrication of polymeric nano-formulations from the lead compounds of Garcinia cowa: characterization and anti-diabetic evaluation (Project id: 2022-1163) (Mentor)
  2. UGC Project- “Isolation, Characterization and Bioactivity Evaluation of Schefflera venulosa (Wight &Arn.) Harms, a folkloric medicine of North East India” (UGC Savitribai Jyotirao Phule Single Girl Child Fellowship, SJSGC 2022-2023; F.No. 82-7/2022(SA-III)) (Mentor)

Ph.D Scholars:

SL

No.

Name of the

Scholars registered

Subject

Research Topic

Date of Registration

Status

1

Kalyani Pathak

Pharmaceutical Sciences

Isolation and Characterization of Bioactive molecule(s) of the Leaves of Annona reticulata Linn., a folklore herbal drug of Assam

29.09.2014

Awarded, 01.11.2019

2

Ejiofor InnocentMary IfedibaluChukwu

Pharmaceutical Sciences

Phytochemical and Pharmacological Investigations of Vernonia amygdalina- A Traditional Medicinal Plant of Nigeria.

07.10.2015

Awarded, 01.07.2019

3

Manash Pratim Pathak

Pharmaceutical Sciences

Pharmacological intervention of Airway Hyperresponsiveness in obese murine model"

07.10.2015

Awarded, 01.04.2021

4

Shyamalendu Nath

Pharmaceutical Sciences

Mining of Biologically Active Molecules from Some Plants Belonging to the Genus Caesalpinia and Elsholtzia from Jorhat and Dibrugarh Districts of Assam.

07.10.2015

Awarded, 01.05.2022

5

Urvashee Gogoi

Pharmaceutical Sciences

Design, Synthesis and Evaluation of Hybrid Xanthone Derivatives as Potential Anti-Cancer Agents.

28.02.2018

On-going

6

Ankita Khataniar

Biotechnology and Bioinformatics

Isolation, Characterization and Bioactivity Evaluation of Schefflera venulosa (Wight & Arn.) Harms, A Traditional Medicine of North East India

12.09.2019

On-going

 

7

Riya Saikia

Pharmaceutical Sciences

In Silico Design, synthesis and Evaluation of Hydroxyxanthone Derivatives As Potential Anti-Diabetic Agents

 

24.09.2020

On-going

8

Pinku Gogoi

Pharmaceutical Sciences

Exploration of Phytochemicals of Dillenia indica L. and Ipomoea aquatica FORSSK. For Development of Potential Anti-Diabetic and Anti-Obesity Compounds

 

24.09.2020

On-going

9

Jon Jyoti Sahariah

Pharmaceutical Sciences

Design, Synthesis and Evaluation of Anti- cancer Activity of Some Hybrid Benzoxanthone Derivatives

 

07.03.2022

On-going

10

Saptasikha Gogoi

Biotechnology and Bioinformatics

Exploration and Evaluation of Therapeutic Potential of Bioactive Compounds from Phyllanthus virgatus G.Forst.

 

19.06.2023

On-going

Past Administrative Assignment:

  • Chairperson, Center for Biotechnology and Bioinformatics, DU

Extension Service:

  • Associated with various Professional bodies

Membership:

  1. Life Member Indian Pharmaceutical Association.
  2. Life Member InPharm Association.

Publications

List of Publications:

  1. Karmakar S, Gogoi U, Saikia R and Das A, Insight into the nutraceutical potential of garcinia species, Curr.Tradit.Med. https://dx.doi.org/10.2174/2215083810666230818092559
  2. Saikia R,Pathak K, Das A, Tayeng D, Ahmed Zaki Md, Das J, Bordoloi S and Pathak Pratim M, Design, QSAR methodology, synthesis and assessment of some structurally different xanthone derivatives as selective Cox-2 inhibitors for their anti-inflammatory properties, Med. Chem. 2023; https://dx.doi.org/10.2174/1573406419666230818092253.
  3. Gogoi, P., Kumar, A., Das, A. et al.Tyrosinase Inhibitory Kinetics, LC-QTOF-MS Based Chemical Profiling and Molecular Docking of Phytochemicals from Dillenia indica L. Chemistry Africa 6, 1799–1810 (2023). https://doi.org/10.1007/s42250-023-00624-4.
  4. Gogoi P.,Kumar A., Dutta N. B.,Das A.& Gakul Baishya (2023) α-Amylase and α-Glucosidase Enzyme Inhibition, Molecular Docking, and Pharmacokinetic Studies of Natural Products from Dilenia indica Barks, Journal of Biologically Active Products from Nature, 13:3, 265-283, DOI: 10.1080/22311866.2023.2234334
  5. Pathak, K., Pathak, M. P., Saikia, R., Gogoi, U., Das, R. J., Patowary, P., Pratim Kashyap, P., Bordoloi, S., Das, J., Sarma, H., Ahmad, M. Z., and Das, A. (Nab). Therapeutic Repurposing Of Antidiabetic Drugs in Diabetes-Associated Comorbidities. Curr. Drug ther., 18. https://doi.org/10.2174/1574885518666230516150404(IF: 0.175)
  6. Das A, Pathak MP, Pathak K, Saikia R and Gogoi U (2023), Herbal Medicine for The Treatment of Obesity-Associated Asthma: A Comprehensive Review. Front. Pharmacol. 14:1186060. https://doi.org/10.3389/fphar.2023.1186060(IF: 5.988)
  7. Ahmad MZ, Pathak K, Das RJ,Saikia R, Sarma H, Gogoi N, Gogoi U,Das A, Alasiri AS, (2023) Design and Optimization of Quercetin-Loaded Polymeric Eudragit L-100 Nanoparticles for Anti-diabetic Activity with Improved Oral Delivery: In-Vitro and In-Vivo Evaluation. J Inorg Organomet Polym. https://doi.org/10.1007/s10904-023-02694-w (IF-3.518)
  1. Pathak M, Pathak K, Saikia R, Gogoi U, Patowary P, Chattopadhyay P, Das A. (2023). Therapeutic Potential of Bioactive Phytoconstituents Found in Fruits in the Treatment of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review. Heliyon. 9. e15347. https://doi.org/10.1016/j.heliyon.2023.e15347(IF: 3.776)
  2. Pathak K, Saikia R, Sarma H, Pathak M, Das R, Gogoi U, Ahmad M, Das A, Abdel-Wahab B. (2023) Nanotheranostics: Application of Nanosensors in Diabetes Management. Journal of Diabetes &Metabolic Disorders. https://doi.org/10.1007/s40200-023-01206-4(IF: 1.23)
  3. Pathak K, Saikia R, Das A.(2023) Unlocking the Therapeutic Potential of Garcinia cowa in Diabetes Management. Sciences of Phytochemistry. 2(1):38-41, https://doi.org/10.58920/sciphy02010038
  4. Paul T, Pathak K, Saikia R, Gogoi U, Sahariah J J and Das A, (2023) The role of medicinal plants in the treatment and management of type 2 diabetes, Current Traditional Medicine; 9: e230223213992 .https://doi.org/10.2174/2215083809666230223164613(IF: 0.162)
  5. Pathak, K, Pathak, M, Saikia, R Gogoi, U, Sahariah, JJ, Das, A, Ahmad, MZ, Paul, T, Das, J, Alqahtani, S. (2023). Cardioprotective Activities of some Indian Spices: An Insight into Pharmacology and Phytochemical Investigation. Current Traditional Medicine. 09. https://doi.org/10.2174/2215083809666230210105442(IF: 0.162)
  6. Khan, S.A, Akhtar, J, Gogoi, U, Meenakshi, D.U, Das, A. (2023) An Overview of1,2,3-Triazole-Containing Hybrids and Their Potential Anticholinesterase Activities. Pharmaceuticals, 16, 179. https://doi.org/10.3390/ph16020179(IF: 6.525)
  7. Ahmad, M.Z.; Alasiri, A.S.; Ahmad, J.; Alqahtani, A.A.; Abdullah, M.M.; Abdel-Wahab, B.A.; Pathak, K.; Saikia, R.; Das, A.; Sarma, H.; Alzahrani, S.A. (2022) Green Synthesis of Titanium Dioxide Nanoparticles Using Ocimum sanctum Leaf Extract: In Vitro Characterization and Its Healing Efficacy in Diabetic Wounds. Molecules, 27, 7712. https://doi.org/10.3390/molecules27227712(IF: 4.927)
  8. Saikia, R, Das, A, Pathak, K, Gogoi, N, Paul, T, Sahariah, JJ, Sarma, H (2022). In Silico Design, Synthesis and Evaluation of Hydroxyxanthone Derivatives as Potential Anti-diabetic Agents Targeting α-glucosidase. Current Enzyme Inhibition. 18. https://doi.org/10.2174/1573408018666220627114552(IF: 0.157)
  9. Gogoi, U., Pathak, K., Saikia, R., Pratim Pathak, M., Paul, T., Alam Khan, S., Das A. (2022)Recent Advances on Natural and Non-natural Xanthones as Potential Anticancer agents: A review. Med Chem..https://doi.org/10.2174/1573406419666221226093311(IF: 2.351)
  10. Pathak, K., Das, R.J., Saika, R., Sahariah, J.J., Pathak, H., Sarma, H., Das, A(2022). Design And Fabrication of Gallic Acid Loaded Chitosan Nano Formulation. Drug Deliv. Lett.https://doi.org/10.2174/2210303112666220512154520(IF: 0.186)
  11. Gogoi, N., Chowdhury, P., Goswami, A.K., Das, A., Chetia, D., Gogoi, B. (2022) Integrated Computational Approach Towards Repurposing of Antimalarial Drug Against SARS-Cov-2 Main Protease. Struct Chem.; 1-14. https://doi.org/10.1007/s11224-022-01916-0(IF. 1.795)
  12. Pathak MP, Pathak K, Saikia R, Gogoi U, Ahmad Md Z, Patowary P and Das A, (2022) Immunomodulatory Effect of Mushrooms and Their Bioactive Compounds in Cancer: A Comprehensive Review, Biomed Pharmacother, 149:112901, https://doi.org/10.1016/j.biopha.2022.112901 (IF: 7.419)
  13. Pathak K, Pathak MP, Saikia R, Gogoi U, Sahariah J J, Zothantluanga H J, Samanta A and Das A, (2022) Cancer Chemotherapy via Natural Bioactive Compounds, Curr Drug DiscovTechnol;19(2):e310322202888https://dx.doi.org/10.2174/1570163819666220331095744(IF: 0.301)
  14. Pathak K, Das R J, Gogoi N, Saikia R, Sarma H and Das A,.(2022) Validated High-Performance Thin Layer Chromatography Method for Simultaneous Determination of Quercetin and Gallic Acid in Annona reticulate , Journal of Planar Chromatography - Modern TLC. https://doi.org/10.1007/s00764-022-00151-x(IF: 1.088)
  15. Nath S, Tamuli K, Saikia S, Narzary B, Gogoi B, Lhouvum N, Dutta D, Sahoo R, Bordoloi M. Das A, Barua I. (2021)Essential Oil from the Leaves of Elsholtzia communis (Collett &Hemsl.) Diels from North East India: Studies on Chemical Profiling, Antimicrobial, Cytotoxic and ACE Inhibitory Activities. Flavour Fragr J.; 36 (6): 626-636. ISSN: 1099-1026(Online) https://doi.org/10.1002/ffj.3677.(IF: 2.5)
  1. Pathak K, Das A, Das R.J. and Sarma H. (2021)Evaluation of Leaf Fraction of Annona reticulate for Antioxidant Activity and Anti-Inflammatory Potential Against Carrageenan Induced Rat Paw Edema Model. Indian Journal of Natural Sciences., 12(68):33877-33888.(IF: 2.452)
  2. Sandilya S, Das A, Deka S, Kalita R. (2021)Synthesis, In-Vivo Anti-Inflammatory Evaluation and Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel Cox-2 Inhibitors., Int J Pharm Sci Res.; Vol. 12(8): 4491-4503., DOI: https://doi.org/10.13040/IJPSR.0975-8232.12(8).4491-03(SJIF: 6.857)
  3. Pathak K, Das RJ. Saikia R, Das A, Ahmad MZ (2021). Bora Rice: Natural polymer for Drug Delivery, Mater. Proc.; 7, 2. https//doi.org/10.3390/IOCPS2021-11290(IF: 1.46)
  4. Gogoi U, Das A, Pathak MP, Chattopadhyay P, Johari S. (2021) Design, Synthesis, Computational and Biological Evaluation of Two New Series of 1, 3-and 1,6-dihydroxyxanthone Derivatives as Selective COX-2 Inhibitors. Lett Drug Des Discov.; 18(9):884-914.(IF: 1.099)
  5. Pathak MP, Patowary P, Das A, Goyary D, Karmakar S, Bhutia YD, Roy P, Das S, Chattopadhyay P (2021). Crosstalk between AdipoR1/AdipoR2 and Nrf2/HO-1 Signal Pathways Activated by β-caryophyllene Suppressed the Compound 48/80 Induced Pseudo-Allergic Reactions. Clin. Exp. Pharmacol.; http://doi.org/10.1111/1440-1681.13555(IF: 2.963)
  6. Pathak MP, Patowary P, Goyary D, Das A, (2021) Chattopadhyay P. β- caryophyllene Ameliorated Obesity-Associated Airway Hyperresponsiveness Through Some Non-Conventional Targets. Phytomedicine; 153610.http://doi.org/10.1016/j.phymed.2021.153610(IF: 6.656)
  7. Nath S, Tamuli KJ,Gogoi B, Bordoloi M, Das A, Barua CC, Barua IC. Antioxidant Properties, Phenolic and Mineral Profiling, Assessment of Angiotensin I Converting Enzyme (ACE) Inhibitory Potential of Elsholtzia communis (Collett &Hemsl.) Diels from North East India. Eur J Integr Med. 2020. Vol: 40, ISSN: 1876-3820(Print) https://doi.org/10.1016/j.eujim.2020.101247(IF-1.314)
  1. Ejiofor II, Das A, Kamaruz Z. Antidiabetic, Anthelmintic and Antioxidation Properties Of Novel and New Phytocompounds Isolated from the Methanolic Stem-Bark of Vernonia amygdalina Delile (Asteraceae). Sci Afr. 2020; 10:e00578. https://doi.org/10.1016/j.sciaf.2020.e00578(IF: 2.134)
  2. Gogoi N, Chetia D, Gogoi B, Das A. Multiple-targets Directed Screening of Flavonoid Compounds from Citrus Species to find out Antimalarial Lead with Predicted Mode of Action: An In Silico and Whole Cell-based In vitro Approach. CurrComput Aided Drug Des.2020;16:https://doi.org/10.2174/1573409916666191226103000(IF: 1.639)
  3. Baruah, V J, Paul R, Gogoi D, Mazumder N, Chakraborty S, Das A, Mondal TK, Sarmah B. Integrated Computational Approach Toward Discovery of Multi-Targeted Natural Products FromThumbai (Leucas aspera) for attuning NKT cells. J Biomol Struct Dyn, 2020; 1-15. https://doi.org10.1080/07391102.2020.1844056(IF: 3.310)
  4. Pathak K, Das A, Shakya A, Saikia R, Sarma H. Evaluation of Anti-Diabetic AndAnti-Hyperlipidemic Activity of Isolated Bioactive Compounds of Leaves of Annona reticulata J. Nat. Prod. 2020; 10:1-8. https://doi.org10.2174/2210315510999200511132940(IF: 4.803)
  5. Pathak MP, Das A, Patowary P, Chattopadhyay P. Continuous Role Of ‘Good Adiponectin’ In Pulmonary and Cardiovascular Diseases: Is Adiponectin Directed Therapy A Boon or A Bane?Biochimie. 2020; 175:1-14.(IF:4.079)
  6. Ejiofor II, Das A, Mir SR, Ali M, Zaman K. Novel Phytocompounds from Vernonia amygdalina with Antimalarial Potentials. Phcog Res. 2020; 12(1):53-59.
  7. Saikia R, Gogoi P, Hore D, Kumar S, Das A. Synthesis and in-vitro evaluation of anti-cancer potential of new hydroxyl derivatives of xanthone. Curr Trends Biotechnol Pharm. 2019; 6(1):105-135.
  8. Das A, Shakya A, Ghosh SK, Singh UP, Bhatt HR. A Review of Phytochemical and Pharmacological Studies of Inula Species. Curr Bioact Compd. 2019; 16(5):557-567.(IF:0.211)
  9. Pathak K, Saikia R, Gogoi U, Das A. Untapped Potential of the Indigenous Anticancer Biodiversity in the Indo-Himalayan hotspot. J. Pharmacogn. 2019; 6(3):85-98.(IF:0.701)
  10. Johari S, Sharma A, Sinha S, Das A. Integrating Pharmacophore Mapping, Virtual Screening, Density Functional Theory, Molecular Simulation Towards The Discovery Of Novel Apolipoprotein (apoE ε4) Inhibitors. Comput Biol Chem. 2019 Apr; 79:83-90.(IF: 3.737)
  11. Borah T, Gogoi B, Khataniar A, Gogoi M, Das A, Borah D. Probiotic characterization of indigenous Bacillus velezensis strain DU14 Isolated from Apong, a Traditionally Fermented Rice Beer of Assam. Biocatal Agric Biotechnol. 2019 Jan; 18:101008. https://doi.org/10.1016/j.bcab.2019.01.046.(IF:0.636)
  12. Pathak K, Das A. Anti-inflammatory Study of Leaf Extracts of Annona reticulata Linn and HPTLC Analysis. Int J Pharma Bio Sci. 2019 Jan; 10(1):68-77.(IF:0.888)
  13. Pathak K, Das A. Assessment of Anti-oxidant Activity of Different Extracts of Annona reticulata Int J Pharm Sci Res. 2018; 9(6):1000-1008.(IF:0.33)
  14. Pathak MP, Policegoudra RS, Goyary D, Das A, Mandal S, Chakraborti S, Bora NS, Islam J, Patowary P, Raju PS, Chattopadhyay P. Safety Evaluation of An Oat Grain Alkaloid Gramine by Genotoxicity Assays. Drug Chem Toxicol. 2018 Apr; 41(2):147-154. (IF:2.597)
  15. Pathak K, Das A. Anti-hyperglycemic activity of Leaves of Annona reticulata Linn on Experimental Rat Diabetic Model. European J. Biomed. Pharm. 2017 Mar; 4(11):674-677.(IF: 6.044)
  16. Ejiofor II, Zaman K, Das A. Effect of Extracts of Vernonia amygdalina in Helminthiasis-A Tropical Neglected Disease. Pharm Res. 2017 Dec; 1(8):000147.(IF: 4.58)
  17. Ejiofor II, Zaman K, Das A. Antidiabetic Evaluations of Different Parts of Vernonia amygdalina. IOSR J Pharm Biol Sci. 2017 Aug; 12(4): 23-28.(IF: 3.83)
  18. Tur J, Badole SD, Cheng F, Das A, Kukreja RC, Tipparaju SM. Corticosteroids and Aldose Reductase Inhibitor EpalrestatModulates Cardiac Action Potential via Kvβ1.1(AKR6A8) subunit of voltage gated potassium channel. Mol Cell Biochem. 2017 Dec; 436(1-2):71-78.(IF: 3.842)
  19. Bhatt HR, Singh UP, Yadav PS, Kumar V, Gahtori P, Das A, Chetia D, Prakash A, Mahanta J. Synthesis, Characterization and Antimalarial Activity of hybrid 4-aminoquinoline-1,3,5-triazine Derivatives. Arab J Chem. 2016; 9:S625-S631.(IF: 6.212)
  20. Bairy PS, Bora NS, Kakoti BB, Das A, Nainwal LM, Gogoi B. Preliminary Phytochemical Screening, In-Vitro Antioxidant Activity, Total Polyphenolic and Flavonoid Content of Garcinia lanceifolia and Citrus maxima (Burm.) Merr. J App Pharm Sci. 2016; 6(9):133-139.(IF: 1.41)
  21. Gahtori P, Pandey R, Kumar V, Ghosh SK, Das A, Kalita JM, Sahu S, Prakash A, Bhattacharyya DR. Toward Resistance-compromised DHFR Inhibitors part 1: Combined Structure/Ligand-Based Virtual Screenings and ADME-Tox Profiling. J Chemom. 2016 Aug; 30(8):1-20.(IF: 2.92)
  22. Das A, Gogoi U, Kalita J, Sandilya S. Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel COX-2 Inhibitors Targeting Prostaglandin Endoperoxide Synthase -2. CurrEnzymInhib. 2016; 12(2):195-204.(IF: 0.157)
  23. Das A, Dutta M, Malakar M. In-silico study, synthesis and biological evaluation of some substituted xanthone derivatives as alpha-glucosidase inhibitor. World J Pharm Sci. 2016 Mar; 4(4): 150-161.(IF: 8.084)
  24. Bairy PS, Das A, Nainwal LM, Mahanta TK, Kumawat MK, Mohapatra PK, Parida P. Design, synthesis and anti-diabetic activity of some novel xanthone derivatives targeting α-glucosidase. Bangladesh J Pharmacol. 2016; 11:308-318.(IF: 0.811)
  25. Bairy PS, Shankar B. Das A. Diabetes mellitus and antidiabetics with reference to Alpha Glucosidase Inhibitors. Asian J Biomed Pharm. 2015; 4(6):10-16.(IF: 9.289)
  26. Shankar B, Das A, Parida P. Design, Molecular Docking Study and Synthesis of 3,6-bis(3′-substituted propoxy)xanthone Derivatives as COX-2 Inhibitors. Asian J. Chem. 2015; 27(12):4634-4640.(IF: 0.158)
  27. Nainwal LM, Parida P, Das A, Bairy PS. Design and Docking Of Novel Series Of Hybrid Xanthones As Anti-Cancer Agent To Target Human DNA topoisomerase 2-alpha. Bangladesh J Pharmacol. 2014; 9:208-217.(IF: 0.811)
  28. Parida P, Kalita S, Shankar B, Yadav RNS, Das A. Homology Modelling and Docking Studies Of Plasmodium Falciparum Telomerase Reverse Transcriptase with Berberine And Some of Its Derivatives. Bangladesh J Pharmacol. 2014; 9:96-104.(IF: 0.811)
  29. Das A, Shaikh M, Jana S. Design, Synthesis and In Vitro Antibacterial Screening of Some Novel 3-Pentyloxy-1-Hydroxyxanthone Derivatives. Med Chem Res. 2014; 23:436-444.(IF: 2.351)
  30. Bairy PS, Das A, Nainwal LM, Shrivastava M. Preliminary Phytochemical Investigation and Anti-inflammatory Activity Studies of Christellaarida leaf extract. Proceedings of International conference cum exhibition on Drug Discovery and Development from Natural Resources. 2014; Feb: 126-133.
  31. Das A, Debnath K, Bairy PS, Nainwal LM. Synthesis and Antimicrobial Screening of a Series of 3,6 bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) Xanthone Derivatives. Curr Trends Biotechnol Pharm. 2013; 2(1):13-23.
  32. Boruah L, Das A, Nainwal LM, Agarwal N, Shankar B. In-Silico Drug Design: A Revolutionary Approach to Change the Concept of Current Drug Discovery Process. Indian J. Pharm. Biol. Res. 2013; June;1(1):60-73.
  33. Das A, Parida P, Agarwal N, Shree J, Shankar B, Chakraborty D. Molecular Docking Study of 3,6 bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) Xanthone Derivatives as PGHS- 2 Inhibitors. J. Appl. Pharm. Sci. 2013 May; 3(4 Suppl.1):S13-S22.(IF: 0.281)
  34. Parida P, Yadav RNS, Shankar B, Chakraborty D, Das A, Singh NK. In-silico Protein Ligand Interaction Study of Typical Antipsychotic Drugs Against Dopaminergic D2 receptor. J. Pharm. Pharm. Sci. 2013; 5(2):183-189.
  35. Jana S, Das A. Synthesis and Assessment of Antibacterial Activity of some Novel 4-Benzyl-piperazinyl-s-triazine Derivatives. Asian J. Chem. 2013; 25(1):186-190.(IF: 0.158)
  36. Singh RB, Das N, Jana S, Das A. Synthesis and In Vitro Antibacterial Screening of some New 2,4,6 Trisubstituted-1,3,5- Triazine Derivatives. Lett Drug Des Discov. 2012; 9:316-321.(IF: 1.099)
  37. Gahtori P, Das A, Mishra R. Design, Synthesis and Antibacterial Activity of Substituted Phenyl Thiazolyl s-Triazines. Pharm. Chem. J. 2011 Jul; 45(4):248-252.(IF: 0.510)
  38. Kaushik A, Kaushik JJ, Das A, Gemal S, Gaim D. Preliminary Studies on anti-inflammatory Activities of Diplazium esculentum in Experimental Animal Models. Int. J. Pharm. Sci. 2011 Apr; 2(5):1251-1253.
  39. Gahtori P, Singh A, Ghosh SK, Das A, Archana U. Synthesis of Some Substituted Phenythiazolyl 1,3,5-Triazine Derivatives. Asian J. Chem. 2011; 23(3):1189-1192.(IF: 0.158)
  40. Singh UP, Das A, Chetia D, Bhattacharya A, Subhaschandra YPK, Kumar V, Bhatt HR, Synthesis and Antibacterial Activity of Some 2,4,6-trisubstituted-1,3,5-triazines. Lat Am J. Pharm. 2010; 29(4):607-611.(IF: 0.229)
  41. Gahtori P, Das A, Bhatt HR. Synthesis and Antibacterial Assessment of N-[4-(4-substituted phenyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-amine. Indian J. Pharm. Sci. 2009 Feb;71(1):79-82. (IF: 0.229)
  42. Das A, Kaushik A, Jyoti J, Veerma R. Anti-inflammatory Activities of Cleome isocandra Seed Oil in Experimental Animal Models. Univ. J. Phytochem. Ayurvedic Heights. 2006 Apr; 2(1):11-13.
  43. Akhtar N, Ali M, Das A. Antibacterial Activity of Inula cuspidate Indian journal Nat. Prod. 2006;22 (3):33-34.(IF: 0.192)
  44. Kaushik A, Kaushik JJ, Das A, Saini V. Antimycotic effects of essential oil of leaves of Artemesia nilagirica Indian Perfumer. 2005 Oct; 49(4): 515-517.

Book Chapters:

  1. Ahmad MZ, Pathak K, Bhatnagar D, Ladhe S, Kumar D, Saikia R, Das A.(2023). Nanotheranostic Approach for Cancer Treatment. In: Rezaei, N. (eds) Handbook of Cancer and Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-80962-1_296-1.
  2. Das, A., Pathak, K., Pathak, M. P., Saikia, R., Gogoi, U., & Acharya, N. S. (2023). Potential of Herbal Drug Delivery in Treating Malaria. In R. Shegokar& Y. Pathak (Eds.), Malarial Drug Delivery Systems (pp. 333–357). Springer International Publishing. https://doi.org/10.1007/978-3-031-15848-3_15
  3. Das, A., Pathak, K., Pratim Pathak, M., Gogoi, U., &Saikia, R. (2023). Nrf2 and the Aging Liver. In K. F. A. Soliman & Y. V. Pathak, Flavonoids and Anti-Aging (1st ed., pp. 203–226). CRC Press. https://doi.org/10.1201/9781003225225-10
  4. Das, A.,Pratim Pathak, M., Pathak, K., Gogoi, U., &Saikia, R. (2023). Changes in the Regulation of Energy Metabolism in Chronic Diseases Using Functional Foods and Nutraceuticals. In Applications of Functional Foods and Nutraceuticals for Chronic Diseases (1st ed., p. 30). CRC Press. https://doi.org/10.1201/9781003220053-9
  5. Pathak, K., Gogoi, U., Saikia, R., Pathak, M. P., &Das, A. (2022). Marine-derived antidiabetic compounds: An insight into their sources, chemistry, SAR, and molecular mechanisms. In Studies in Natural Products Chemistry (Vol. 73, pp. 467–504). Elsevier. https://doi.org/10.1016/B978-0-323-91097-2.00004-2
  6. Saikia, S., Das, A., & Pathak, Y. Y. (2022). Gold nanoparticles in cancer theranostics. In Nanocarriers for Drug-Targeting Brain Tumors (pp. 513–526). Elsevier. https://doi.org/10.1016/B978-0-323-90773-6.00010-5
  7. Saikia, S., Das, A., Pathak, Y., & Islam, N. (2021). Drug Delivery Using Aerosols: Challenges and Advances in Neonatal Pediatric Subgroup. In Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences (1st ed.). CRC Press. https://doi.org/10.1201/9781003046547
  8. Das, A., Saikia, R., Pathak, K., Gogoi, U., &Saikia, S. (2021). Chronic Lung Diseases: Treatment, Challenges, and Solutions. In Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences (1st ed.). CRC Press. https://doi.org/10.1201/9781003046547
  9. Das, A., Pathak, M. P., Patowary, P., & Das, S. (2021). Introduction to Lung Physiology from a Drug Delivery Perspective. In Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences (1st ed.). CRC Press. https://doi.org/10.1201/9781003046547
  10. Pathak, K., Pathak, M. P., Gogoi, U., Saikia, R., &Das, A. (2021). COVID19: Preventive and Protective Control Management Strategies. In J.-M. Sabatier (Ed.), Coronaviruses (Vol. 2, pp. 32–62). BENTHAM SCIENCE PUBLISHERS. https://doi.org/10.2174/9789814998604121020004
  11. Das, A., Saikia, R., Pathak, K., Gogoi, U., & Pathak, M. P. (2020). Anti-diabetic Nano-formulation from Herbal Source. In M. K. Das & Y. V. Pathak (Eds.), Nano Medicine and Nano Safety (pp. 61–84). Springer Singapore. https://doi.org/10.1007/978-981-15-6255-6_4
  12. Das, A., Pathak, K., Pathak, M. P., Chattopadhyay, P., Saikia, R., & Sahu, S. (2020). Enzyme Inhibition. In Recent advances in pharmaceutical sciences (1st ed., pp. 1–37). essay, Akinik Publications, ISBN: 9789353355548
  13. Pathak, Y. V., Ardekani, A. M., Das, A., Pathak, M. P., Chattopadhyay, P., & Pathak, Y. V. (2017). Gene-Based Dietary Advice and Eating Behavior. In Nutrigenomics and nutraceuticals clinical relevance and disease prevention (1st ed., pp. 515–528). essay, CRC Press, https://doi.org/10.1201/9781315153711-21
Profile

Profile

Education:

  1. Bachelor’s Degree : B.Pharm (Dibrugarh University)
  2. Master’s Degree : M.Pharm (Birla Institute of Technology, Mesra, Ranchi)
  3. Ph.D.: Pharmaceutical Sciences (Dibrugarh University)
  4. Other: PDCR (Catalyst Clinical Services, New Delhi), Post Doc (USF-Health)

Professional Experience:

  • 25 Years in Teaching & Research

Areas of Interest/ Specialization:

  • Medicinal Chemistry/ Drug Discovery and Development

RESEARCH PROJECTS:

Projects Completed as PI:

  1. AICTE funded RPS Project entitled “Phytochemical and Pharmacological Screening of the fruits of Garcinia cowa with special reference to Antidiarrhoeal activity”. (PI)
  2. AICTE funded RPS-NER Project entitled “Design, synthesis and characterization of topoisomerase II alpha xanthone inhibitors and their chemotherapeutic polymeric nano carriers for the treatment of colorectal cancer”. (PI)

Research Project Completed as Co-PI: DBT Funded:

  1. Synthesis of hybrid class phenylthiazole 1, 3, 5-triazine derivatives as novel antimalarial for Pf-DHFR-TS inhibition.

Research Project Completed as Mentor:

  1. ICMR RA Project entitled “Isolation and characterization of the active principles of leaves of Annona reticulate And their encapsulation into polymeric nanostructured drug delivery system for the treatment of Diabetes”F.No. 45/10/2018/TM/BMS (Mentor)
  2. Design, Synthesis and Evaluation of hybrid xanthone derivatives as potential anti-cancer agents. (UGC National Fellowship) F.No.61-1/2019 (SA-III)(Mentor)

Research Project Ongoing as Mentor:

  1. DHR-Women Scientist A project titled “Fabrication of polymeric nano-formulations from the lead compounds of Garcinia cowa: characterization and anti-diabetic evaluation (Project id: 2022-1163) (Mentor)
  2. UGC Project- “Isolation, Characterization and Bioactivity Evaluation of Schefflera venulosa (Wight &Arn.) Harms, a folkloric medicine of North East India” (UGC Savitribai Jyotirao Phule Single Girl Child Fellowship, SJSGC 2022-2023; F.No. 82-7/2022(SA-III)) (Mentor)

Ph.D Scholars:

SL

No.

Name of the

Scholars registered

Subject

Research Topic

Date of Registration

Status

1

Kalyani Pathak

Pharmaceutical Sciences

Isolation and Characterization of Bioactive molecule(s) of the Leaves of Annona reticulata Linn., a folklore herbal drug of Assam

29.09.2014

Awarded, 01.11.2019

2

Ejiofor InnocentMary IfedibaluChukwu

Pharmaceutical Sciences

Phytochemical and Pharmacological Investigations of Vernonia amygdalina- A Traditional Medicinal Plant of Nigeria.

07.10.2015

Awarded, 01.07.2019

3

Manash Pratim Pathak

Pharmaceutical Sciences

Pharmacological intervention of Airway Hyperresponsiveness in obese murine model"

07.10.2015

Awarded, 01.04.2021

4

Shyamalendu Nath

Pharmaceutical Sciences

Mining of Biologically Active Molecules from Some Plants Belonging to the Genus Caesalpinia and Elsholtzia from Jorhat and Dibrugarh Districts of Assam.

07.10.2015

Awarded, 01.05.2022

5

Urvashee Gogoi

Pharmaceutical Sciences

Design, Synthesis and Evaluation of Hybrid Xanthone Derivatives as Potential Anti-Cancer Agents.

28.02.2018

On-going

6

Ankita Khataniar

Biotechnology and Bioinformatics

Isolation, Characterization and Bioactivity Evaluation of Schefflera venulosa (Wight & Arn.) Harms, A Traditional Medicine of North East India

12.09.2019

On-going

 

7

Riya Saikia

Pharmaceutical Sciences

In Silico Design, synthesis and Evaluation of Hydroxyxanthone Derivatives As Potential Anti-Diabetic Agents

 

24.09.2020

On-going

8

Pinku Gogoi

Pharmaceutical Sciences

Exploration of Phytochemicals of Dillenia indica L. and Ipomoea aquatica FORSSK. For Development of Potential Anti-Diabetic and Anti-Obesity Compounds

 

24.09.2020

On-going

9

Jon Jyoti Sahariah

Pharmaceutical Sciences

Design, Synthesis and Evaluation of Anti- cancer Activity of Some Hybrid Benzoxanthone Derivatives

 

07.03.2022

On-going

10

Saptasikha Gogoi

Biotechnology and Bioinformatics

Exploration and Evaluation of Therapeutic Potential of Bioactive Compounds from Phyllanthus virgatus G.Forst.

 

19.06.2023

On-going

Past Administrative Assignment:

  • Chairperson, Center for Biotechnology and Bioinformatics, DU

Extension Service:

  • Associated with various Professional bodies

Membership:

  1. Life Member Indian Pharmaceutical Association.
  2. Life Member InPharm Association.
Publications

Publications

 

List of Publications:

  1. Karmakar S, Gogoi U, Saikia R and Das A, Insight into the nutraceutical potential of garcinia species, Curr.Tradit.Med. https://dx.doi.org/10.2174/2215083810666230818092559
  2. Saikia R,Pathak K, Das A, Tayeng D, Ahmed Zaki Md, Das J, Bordoloi S and Pathak Pratim M, Design, QSAR methodology, synthesis and assessment of some structurally different xanthone derivatives as selective Cox-2 inhibitors for their anti-inflammatory properties, Med. Chem. 2023; https://dx.doi.org/10.2174/1573406419666230818092253.
  3. Gogoi, P., Kumar, A., Das, A. et al.Tyrosinase Inhibitory Kinetics, LC-QTOF-MS Based Chemical Profiling and Molecular Docking of Phytochemicals from Dillenia indica L. Chemistry Africa 6, 1799–1810 (2023). https://doi.org/10.1007/s42250-023-00624-4.
  4. Gogoi P.,Kumar A., Dutta N. B.,Das A.& Gakul Baishya (2023) α-Amylase and α-Glucosidase Enzyme Inhibition, Molecular Docking, and Pharmacokinetic Studies of Natural Products from Dilenia indica Barks, Journal of Biologically Active Products from Nature, 13:3, 265-283, DOI: 10.1080/22311866.2023.2234334
  5. Pathak, K., Pathak, M. P., Saikia, R., Gogoi, U., Das, R. J., Patowary, P., Pratim Kashyap, P., Bordoloi, S., Das, J., Sarma, H., Ahmad, M. Z., and Das, A. (Nab). Therapeutic Repurposing Of Antidiabetic Drugs in Diabetes-Associated Comorbidities. Curr. Drug ther., 18. https://doi.org/10.2174/1574885518666230516150404(IF: 0.175)
  6. Das A, Pathak MP, Pathak K, Saikia R and Gogoi U (2023), Herbal Medicine for The Treatment of Obesity-Associated Asthma: A Comprehensive Review. Front. Pharmacol. 14:1186060. https://doi.org/10.3389/fphar.2023.1186060(IF: 5.988)
  7. Ahmad MZ, Pathak K, Das RJ,Saikia R, Sarma H, Gogoi N, Gogoi U,Das A, Alasiri AS, (2023) Design and Optimization of Quercetin-Loaded Polymeric Eudragit L-100 Nanoparticles for Anti-diabetic Activity with Improved Oral Delivery: In-Vitro and In-Vivo Evaluation. J Inorg Organomet Polym. https://doi.org/10.1007/s10904-023-02694-w (IF-3.518)
  1. Pathak M, Pathak K, Saikia R, Gogoi U, Patowary P, Chattopadhyay P, Das A. (2023). Therapeutic Potential of Bioactive Phytoconstituents Found in Fruits in the Treatment of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review. Heliyon. 9. e15347. https://doi.org/10.1016/j.heliyon.2023.e15347(IF: 3.776)
  2. Pathak K, Saikia R, Sarma H, Pathak M, Das R, Gogoi U, Ahmad M, Das A, Abdel-Wahab B. (2023) Nanotheranostics: Application of Nanosensors in Diabetes Management. Journal of Diabetes &Metabolic Disorders. https://doi.org/10.1007/s40200-023-01206-4(IF: 1.23)
  3. Pathak K, Saikia R, Das A.(2023) Unlocking the Therapeutic Potential of Garcinia cowa in Diabetes Management. Sciences of Phytochemistry. 2(1):38-41, https://doi.org/10.58920/sciphy02010038
  4. Paul T, Pathak K, Saikia R, Gogoi U, Sahariah J J and Das A, (2023) The role of medicinal plants in the treatment and management of type 2 diabetes, Current Traditional Medicine; 9: e230223213992 .https://doi.org/10.2174/2215083809666230223164613(IF: 0.162)
  5. Pathak, K, Pathak, M, Saikia, R Gogoi, U, Sahariah, JJ, Das, A, Ahmad, MZ, Paul, T, Das, J, Alqahtani, S. (2023). Cardioprotective Activities of some Indian Spices: An Insight into Pharmacology and Phytochemical Investigation. Current Traditional Medicine. 09. https://doi.org/10.2174/2215083809666230210105442(IF: 0.162)
  6. Khan, S.A, Akhtar, J, Gogoi, U, Meenakshi, D.U, Das, A. (2023) An Overview of1,2,3-Triazole-Containing Hybrids and Their Potential Anticholinesterase Activities. Pharmaceuticals, 16, 179. https://doi.org/10.3390/ph16020179(IF: 6.525)
  7. Ahmad, M.Z.; Alasiri, A.S.; Ahmad, J.; Alqahtani, A.A.; Abdullah, M.M.; Abdel-Wahab, B.A.; Pathak, K.; Saikia, R.; Das, A.; Sarma, H.; Alzahrani, S.A. (2022) Green Synthesis of Titanium Dioxide Nanoparticles Using Ocimum sanctum Leaf Extract: In Vitro Characterization and Its Healing Efficacy in Diabetic Wounds. Molecules, 27, 7712. https://doi.org/10.3390/molecules27227712(IF: 4.927)
  8. Saikia, R, Das, A, Pathak, K, Gogoi, N, Paul, T, Sahariah, JJ, Sarma, H (2022). In Silico Design, Synthesis and Evaluation of Hydroxyxanthone Derivatives as Potential Anti-diabetic Agents Targeting α-glucosidase. Current Enzyme Inhibition. 18. https://doi.org/10.2174/1573408018666220627114552(IF: 0.157)
  9. Gogoi, U., Pathak, K., Saikia, R., Pratim Pathak, M., Paul, T., Alam Khan, S., Das A. (2022)Recent Advances on Natural and Non-natural Xanthones as Potential Anticancer agents: A review. Med Chem..https://doi.org/10.2174/1573406419666221226093311(IF: 2.351)
  10. Pathak, K., Das, R.J., Saika, R., Sahariah, J.J., Pathak, H., Sarma, H., Das, A(2022). Design And Fabrication of Gallic Acid Loaded Chitosan Nano Formulation. Drug Deliv. Lett.https://doi.org/10.2174/2210303112666220512154520(IF: 0.186)
  11. Gogoi, N., Chowdhury, P., Goswami, A.K., Das, A., Chetia, D., Gogoi, B. (2022) Integrated Computational Approach Towards Repurposing of Antimalarial Drug Against SARS-Cov-2 Main Protease. Struct Chem.; 1-14. https://doi.org/10.1007/s11224-022-01916-0(IF. 1.795)
  12. Pathak MP, Pathak K, Saikia R, Gogoi U, Ahmad Md Z, Patowary P and Das A, (2022) Immunomodulatory Effect of Mushrooms and Their Bioactive Compounds in Cancer: A Comprehensive Review, Biomed Pharmacother, 149:112901, https://doi.org/10.1016/j.biopha.2022.112901 (IF: 7.419)
  13. Pathak K, Pathak MP, Saikia R, Gogoi U, Sahariah J J, Zothantluanga H J, Samanta A and Das A, (2022) Cancer Chemotherapy via Natural Bioactive Compounds, Curr Drug DiscovTechnol;19(2):e310322202888https://dx.doi.org/10.2174/1570163819666220331095744(IF: 0.301)
  14. Pathak K, Das R J, Gogoi N, Saikia R, Sarma H and Das A,.(2022) Validated High-Performance Thin Layer Chromatography Method for Simultaneous Determination of Quercetin and Gallic Acid in Annona reticulate , Journal of Planar Chromatography - Modern TLC. https://doi.org/10.1007/s00764-022-00151-x(IF: 1.088)
  15. Nath S, Tamuli K, Saikia S, Narzary B, Gogoi B, Lhouvum N, Dutta D, Sahoo R, Bordoloi M. Das A, Barua I. (2021)Essential Oil from the Leaves of Elsholtzia communis (Collett &Hemsl.) Diels from North East India: Studies on Chemical Profiling, Antimicrobial, Cytotoxic and ACE Inhibitory Activities. Flavour Fragr J.; 36 (6): 626-636. ISSN: 1099-1026(Online) https://doi.org/10.1002/ffj.3677.(IF: 2.5)
  1. Pathak K, Das A, Das R.J. and Sarma H. (2021)Evaluation of Leaf Fraction of Annona reticulate for Antioxidant Activity and Anti-Inflammatory Potential Against Carrageenan Induced Rat Paw Edema Model. Indian Journal of Natural Sciences., 12(68):33877-33888.(IF: 2.452)
  2. Sandilya S, Das A, Deka S, Kalita R. (2021)Synthesis, In-Vivo Anti-Inflammatory Evaluation and Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel Cox-2 Inhibitors., Int J Pharm Sci Res.; Vol. 12(8): 4491-4503., DOI: https://doi.org/10.13040/IJPSR.0975-8232.12(8).4491-03(SJIF: 6.857)
  3. Pathak K, Das RJ. Saikia R, Das A, Ahmad MZ (2021). Bora Rice: Natural polymer for Drug Delivery, Mater. Proc.; 7, 2. https//doi.org/10.3390/IOCPS2021-11290(IF: 1.46)
  4. Gogoi U, Das A, Pathak MP, Chattopadhyay P, Johari S. (2021) Design, Synthesis, Computational and Biological Evaluation of Two New Series of 1, 3-and 1,6-dihydroxyxanthone Derivatives as Selective COX-2 Inhibitors. Lett Drug Des Discov.; 18(9):884-914.(IF: 1.099)
  5. Pathak MP, Patowary P, Das A, Goyary D, Karmakar S, Bhutia YD, Roy P, Das S, Chattopadhyay P (2021). Crosstalk between AdipoR1/AdipoR2 and Nrf2/HO-1 Signal Pathways Activated by β-caryophyllene Suppressed the Compound 48/80 Induced Pseudo-Allergic Reactions. Clin. Exp. Pharmacol.; http://doi.org/10.1111/1440-1681.13555(IF: 2.963)
  6. Pathak MP, Patowary P, Goyary D, Das A, (2021) Chattopadhyay P. β- caryophyllene Ameliorated Obesity-Associated Airway Hyperresponsiveness Through Some Non-Conventional Targets. Phytomedicine; 153610.http://doi.org/10.1016/j.phymed.2021.153610(IF: 6.656)
  7. Nath S, Tamuli KJ,Gogoi B, Bordoloi M, Das A, Barua CC, Barua IC. Antioxidant Properties, Phenolic and Mineral Profiling, Assessment of Angiotensin I Converting Enzyme (ACE) Inhibitory Potential of Elsholtzia communis (Collett &Hemsl.) Diels from North East India. Eur J Integr Med. 2020. Vol: 40, ISSN: 1876-3820(Print) https://doi.org/10.1016/j.eujim.2020.101247(IF-1.314)
  1. Ejiofor II, Das A, Kamaruz Z. Antidiabetic, Anthelmintic and Antioxidation Properties Of Novel and New Phytocompounds Isolated from the Methanolic Stem-Bark of Vernonia amygdalina Delile (Asteraceae). Sci Afr. 2020; 10:e00578. https://doi.org/10.1016/j.sciaf.2020.e00578(IF: 2.134)
  2. Gogoi N, Chetia D, Gogoi B, Das A. Multiple-targets Directed Screening of Flavonoid Compounds from Citrus Species to find out Antimalarial Lead with Predicted Mode of Action: An In Silico and Whole Cell-based In vitro Approach. CurrComput Aided Drug Des.2020;16:https://doi.org/10.2174/1573409916666191226103000(IF: 1.639)
  3. Baruah, V J, Paul R, Gogoi D, Mazumder N, Chakraborty S, Das A, Mondal TK, Sarmah B. Integrated Computational Approach Toward Discovery of Multi-Targeted Natural Products FromThumbai (Leucas aspera) for attuning NKT cells. J Biomol Struct Dyn, 2020; 1-15. https://doi.org10.1080/07391102.2020.1844056(IF: 3.310)
  4. Pathak K, Das A, Shakya A, Saikia R, Sarma H. Evaluation of Anti-Diabetic AndAnti-Hyperlipidemic Activity of Isolated Bioactive Compounds of Leaves of Annona reticulata J. Nat. Prod. 2020; 10:1-8. https://doi.org10.2174/2210315510999200511132940(IF: 4.803)
  5. Pathak MP, Das A, Patowary P, Chattopadhyay P. Continuous Role Of ‘Good Adiponectin’ In Pulmonary and Cardiovascular Diseases: Is Adiponectin Directed Therapy A Boon or A Bane?Biochimie. 2020; 175:1-14.(IF:4.079)
  6. Ejiofor II, Das A, Mir SR, Ali M, Zaman K. Novel Phytocompounds from Vernonia amygdalina with Antimalarial Potentials. Phcog Res. 2020; 12(1):53-59.
  7. Saikia R, Gogoi P, Hore D, Kumar S, Das A. Synthesis and in-vitro evaluation of anti-cancer potential of new hydroxyl derivatives of xanthone. Curr Trends Biotechnol Pharm. 2019; 6(1):105-135.
  8. Das A, Shakya A, Ghosh SK, Singh UP, Bhatt HR. A Review of Phytochemical and Pharmacological Studies of Inula Species. Curr Bioact Compd. 2019; 16(5):557-567.(IF:0.211)
  9. Pathak K, Saikia R, Gogoi U, Das A. Untapped Potential of the Indigenous Anticancer Biodiversity in the Indo-Himalayan hotspot. J. Pharmacogn. 2019; 6(3):85-98.(IF:0.701)
  10. Johari S, Sharma A, Sinha S, Das A. Integrating Pharmacophore Mapping, Virtual Screening, Density Functional Theory, Molecular Simulation Towards The Discovery Of Novel Apolipoprotein (apoE ε4) Inhibitors. Comput Biol Chem. 2019 Apr; 79:83-90.(IF: 3.737)
  11. Borah T, Gogoi B, Khataniar A, Gogoi M, Das A, Borah D. Probiotic characterization of indigenous Bacillus velezensis strain DU14 Isolated from Apong, a Traditionally Fermented Rice Beer of Assam. Biocatal Agric Biotechnol. 2019 Jan; 18:101008. https://doi.org/10.1016/j.bcab.2019.01.046.(IF:0.636)
  12. Pathak K, Das A. Anti-inflammatory Study of Leaf Extracts of Annona reticulata Linn and HPTLC Analysis. Int J Pharma Bio Sci. 2019 Jan; 10(1):68-77.(IF:0.888)
  13. Pathak K, Das A. Assessment of Anti-oxidant Activity of Different Extracts of Annona reticulata Int J Pharm Sci Res. 2018; 9(6):1000-1008.(IF:0.33)
  14. Pathak MP, Policegoudra RS, Goyary D, Das A, Mandal S, Chakraborti S, Bora NS, Islam J, Patowary P, Raju PS, Chattopadhyay P. Safety Evaluation of An Oat Grain Alkaloid Gramine by Genotoxicity Assays. Drug Chem Toxicol. 2018 Apr; 41(2):147-154. (IF:2.597)
  15. Pathak K, Das A. Anti-hyperglycemic activity of Leaves of Annona reticulata Linn on Experimental Rat Diabetic Model. European J. Biomed. Pharm. 2017 Mar; 4(11):674-677.(IF: 6.044)
  16. Ejiofor II, Zaman K, Das A. Effect of Extracts of Vernonia amygdalina in Helminthiasis-A Tropical Neglected Disease. Pharm Res. 2017 Dec; 1(8):000147.(IF: 4.58)
  17. Ejiofor II, Zaman K, Das A. Antidiabetic Evaluations of Different Parts of Vernonia amygdalina. IOSR J Pharm Biol Sci. 2017 Aug; 12(4): 23-28.(IF: 3.83)
  18. Tur J, Badole SD, Cheng F, Das A, Kukreja RC, Tipparaju SM. Corticosteroids and Aldose Reductase Inhibitor EpalrestatModulates Cardiac Action Potential via Kvβ1.1(AKR6A8) subunit of voltage gated potassium channel. Mol Cell Biochem. 2017 Dec; 436(1-2):71-78.(IF: 3.842)
  19. Bhatt HR, Singh UP, Yadav PS, Kumar V, Gahtori P, Das A, Chetia D, Prakash A, Mahanta J. Synthesis, Characterization and Antimalarial Activity of hybrid 4-aminoquinoline-1,3,5-triazine Derivatives. Arab J Chem. 2016; 9:S625-S631.(IF: 6.212)
  20. Bairy PS, Bora NS, Kakoti BB, Das A, Nainwal LM, Gogoi B. Preliminary Phytochemical Screening, In-Vitro Antioxidant Activity, Total Polyphenolic and Flavonoid Content of Garcinia lanceifolia and Citrus maxima (Burm.) Merr. J App Pharm Sci. 2016; 6(9):133-139.(IF: 1.41)
  21. Gahtori P, Pandey R, Kumar V, Ghosh SK, Das A, Kalita JM, Sahu S, Prakash A, Bhattacharyya DR. Toward Resistance-compromised DHFR Inhibitors part 1: Combined Structure/Ligand-Based Virtual Screenings and ADME-Tox Profiling. J Chemom. 2016 Aug; 30(8):1-20.(IF: 2.92)
  22. Das A, Gogoi U, Kalita J, Sandilya S. Molecular Docking Study of a Series of Substituted Xanthone Derivatives as Novel COX-2 Inhibitors Targeting Prostaglandin Endoperoxide Synthase -2. CurrEnzymInhib. 2016; 12(2):195-204.(IF: 0.157)
  23. Das A, Dutta M, Malakar M. In-silico study, synthesis and biological evaluation of some substituted xanthone derivatives as alpha-glucosidase inhibitor. World J Pharm Sci. 2016 Mar; 4(4): 150-161.(IF: 8.084)
  24. Bairy PS, Das A, Nainwal LM, Mahanta TK, Kumawat MK, Mohapatra PK, Parida P. Design, synthesis and anti-diabetic activity of some novel xanthone derivatives targeting α-glucosidase. Bangladesh J Pharmacol. 2016; 11:308-318.(IF: 0.811)
  25. Bairy PS, Shankar B. Das A. Diabetes mellitus and antidiabetics with reference to Alpha Glucosidase Inhibitors. Asian J Biomed Pharm. 2015; 4(6):10-16.(IF: 9.289)
  26. Shankar B, Das A, Parida P. Design, Molecular Docking Study and Synthesis of 3,6-bis(3′-substituted propoxy)xanthone Derivatives as COX-2 Inhibitors. Asian J. Chem. 2015; 27(12):4634-4640.(IF: 0.158)
  27. Nainwal LM, Parida P, Das A, Bairy PS. Design and Docking Of Novel Series Of Hybrid Xanthones As Anti-Cancer Agent To Target Human DNA topoisomerase 2-alpha. Bangladesh J Pharmacol. 2014; 9:208-217.(IF: 0.811)
  28. Parida P, Kalita S, Shankar B, Yadav RNS, Das A. Homology Modelling and Docking Studies Of Plasmodium Falciparum Telomerase Reverse Transcriptase with Berberine And Some of Its Derivatives. Bangladesh J Pharmacol. 2014; 9:96-104.(IF: 0.811)
  29. Das A, Shaikh M, Jana S. Design, Synthesis and In Vitro Antibacterial Screening of Some Novel 3-Pentyloxy-1-Hydroxyxanthone Derivatives. Med Chem Res. 2014; 23:436-444.(IF: 2.351)
  30. Bairy PS, Das A, Nainwal LM, Shrivastava M. Preliminary Phytochemical Investigation and Anti-inflammatory Activity Studies of Christellaarida leaf extract. Proceedings of International conference cum exhibition on Drug Discovery and Development from Natural Resources. 2014; Feb: 126-133.
  31. Das A, Debnath K, Bairy PS, Nainwal LM. Synthesis and Antimicrobial Screening of a Series of 3,6 bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) Xanthone Derivatives. Curr Trends Biotechnol Pharm. 2013; 2(1):13-23.
  32. Boruah L, Das A, Nainwal LM, Agarwal N, Shankar B. In-Silico Drug Design: A Revolutionary Approach to Change the Concept of Current Drug Discovery Process. Indian J. Pharm. Biol. Res. 2013; June;1(1):60-73.
  33. Das A, Parida P, Agarwal N, Shree J, Shankar B, Chakraborty D. Molecular Docking Study of 3,6 bis(3’substituted propoxy) and 3,6 bis (5’substitutedpentyloxy) Xanthone Derivatives as PGHS- 2 Inhibitors. J. Appl. Pharm. Sci. 2013 May; 3(4 Suppl.1):S13-S22.(IF: 0.281)
  34. Parida P, Yadav RNS, Shankar B, Chakraborty D, Das A, Singh NK. In-silico Protein Ligand Interaction Study of Typical Antipsychotic Drugs Against Dopaminergic D2 receptor. J. Pharm. Pharm. Sci. 2013; 5(2):183-189.
  35. Jana S, Das A. Synthesis and Assessment of Antibacterial Activity of some Novel 4-Benzyl-piperazinyl-s-triazine Derivatives. Asian J. Chem. 2013; 25(1):186-190.(IF: 0.158)
  36. Singh RB, Das N, Jana S, Das A. Synthesis and In Vitro Antibacterial Screening of some New 2,4,6 Trisubstituted-1,3,5- Triazine Derivatives. Lett Drug Des Discov. 2012; 9:316-321.(IF: 1.099)
  37. Gahtori P, Das A, Mishra R. Design, Synthesis and Antibacterial Activity of Substituted Phenyl Thiazolyl s-Triazines. Pharm. Chem. J. 2011 Jul; 45(4):248-252.(IF: 0.510)
  38. Kaushik A, Kaushik JJ, Das A, Gemal S, Gaim D. Preliminary Studies on anti-inflammatory Activities of Diplazium esculentum in Experimental Animal Models. Int. J. Pharm. Sci. 2011 Apr; 2(5):1251-1253.
  39. Gahtori P, Singh A, Ghosh SK, Das A, Archana U. Synthesis of Some Substituted Phenythiazolyl 1,3,5-Triazine Derivatives. Asian J. Chem. 2011; 23(3):1189-1192.(IF: 0.158)
  40. Singh UP, Das A, Chetia D, Bhattacharya A, Subhaschandra YPK, Kumar V, Bhatt HR, Synthesis and Antibacterial Activity of Some 2,4,6-trisubstituted-1,3,5-triazines. Lat Am J. Pharm. 2010; 29(4):607-611.(IF: 0.229)
  41. Gahtori P, Das A, Bhatt HR. Synthesis and Antibacterial Assessment of N-[4-(4-substituted phenyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-amine. Indian J. Pharm. Sci. 2009 Feb;71(1):79-82. (IF: 0.229)
  42. Das A, Kaushik A, Jyoti J, Veerma R. Anti-inflammatory Activities of Cleome isocandra Seed Oil in Experimental Animal Models. Univ. J. Phytochem. Ayurvedic Heights. 2006 Apr; 2(1):11-13.
  43. Akhtar N, Ali M, Das A. Antibacterial Activity of Inula cuspidate Indian journal Nat. Prod. 2006;22 (3):33-34.(IF: 0.192)
  44. Kaushik A, Kaushik JJ, Das A, Saini V. Antimycotic effects of essential oil of leaves of Artemesia nilagirica Indian Perfumer. 2005 Oct; 49(4): 515-517.

Book Chapters:

  1. Ahmad MZ, Pathak K, Bhatnagar D, Ladhe S, Kumar D, Saikia R, Das A.(2023). Nanotheranostic Approach for Cancer Treatment. In: Rezaei, N. (eds) Handbook of Cancer and Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-80962-1_296-1.
  2. Das, A., Pathak, K., Pathak, M. P., Saikia, R., Gogoi, U., & Acharya, N. S. (2023). Potential of Herbal Drug Delivery in Treating Malaria. In R. Shegokar& Y. Pathak (Eds.), Malarial Drug Delivery Systems (pp. 333–357). Springer International Publishing. https://doi.org/10.1007/978-3-031-15848-3_15
  3. Das, A., Pathak, K., Pratim Pathak, M., Gogoi, U., &Saikia, R. (2023). Nrf2 and the Aging Liver. In K. F. A. Soliman & Y. V. Pathak, Flavonoids and Anti-Aging (1st ed., pp. 203–226). CRC Press. https://doi.org/10.1201/9781003225225-10
  4. Das, A.,Pratim Pathak, M., Pathak, K., Gogoi, U., &Saikia, R. (2023). Changes in the Regulation of Energy Metabolism in Chronic Diseases Using Functional Foods and Nutraceuticals. In Applications of Functional Foods and Nutraceuticals for Chronic Diseases (1st ed., p. 30). CRC Press. https://doi.org/10.1201/9781003220053-9
  5. Pathak, K., Gogoi, U., Saikia, R., Pathak, M. P., &Das, A. (2022). Marine-derived antidiabetic compounds: An insight into their sources, chemistry, SAR, and molecular mechanisms. In Studies in Natural Products Chemistry (Vol. 73, pp. 467–504). Elsevier. https://doi.org/10.1016/B978-0-323-91097-2.00004-2
  6. Saikia, S., Das, A., & Pathak, Y. Y. (2022). Gold nanoparticles in cancer theranostics. In Nanocarriers for Drug-Targeting Brain Tumors (pp. 513–526). Elsevier. https://doi.org/10.1016/B978-0-323-90773-6.00010-5
  7. Saikia, S., Das, A., Pathak, Y., & Islam, N. (2021). Drug Delivery Using Aerosols: Challenges and Advances in Neonatal Pediatric Subgroup. In Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences (1st ed.). CRC Press. https://doi.org/10.1201/9781003046547
  8. Das, A., Saikia, R., Pathak, K., Gogoi, U., &Saikia, S. (2021). Chronic Lung Diseases: Treatment, Challenges, and Solutions. In Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences (1st ed.). CRC Press. https://doi.org/10.1201/9781003046547
  9. Das, A., Pathak, M. P., Patowary, P., & Das, S. (2021). Introduction to Lung Physiology from a Drug Delivery Perspective. In Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences (1st ed.). CRC Press. https://doi.org/10.1201/9781003046547
  10. Pathak, K., Pathak, M. P., Gogoi, U., Saikia, R., &Das, A. (2021). COVID19: Preventive and Protective Control Management Strategies. In J.-M. Sabatier (Ed.), Coronaviruses (Vol. 2, pp. 32–62). BENTHAM SCIENCE PUBLISHERS. https://doi.org/10.2174/9789814998604121020004
  11. Das, A., Saikia, R., Pathak, K., Gogoi, U., & Pathak, M. P. (2020). Anti-diabetic Nano-formulation from Herbal Source. In M. K. Das & Y. V. Pathak (Eds.), Nano Medicine and Nano Safety (pp. 61–84). Springer Singapore. https://doi.org/10.1007/978-981-15-6255-6_4
  12. Das, A., Pathak, K., Pathak, M. P., Chattopadhyay, P., Saikia, R., & Sahu, S. (2020). Enzyme Inhibition. In Recent advances in pharmaceutical sciences (1st ed., pp. 1–37). essay, Akinik Publications, ISBN: 9789353355548
  13. Pathak, Y. V., Ardekani, A. M., Das, A., Pathak, M. P., Chattopadhyay, P., & Pathak, Y. V. (2017). Gene-Based Dietary Advice and Eating Behavior. In Nutrigenomics and nutraceuticals clinical relevance and disease prevention (1st ed., pp. 515–528). essay, CRC Press, https://doi.org/10.1201/9781315153711-21
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