Dr. Dipak Chetia

Dr. Dipak Chetia
Dr. Dipak Chetia
...
0373-2370254
Professor
Pharmaceutical Science

Profile

Education:

  1. Bachelor’s Degree: B. Sc., B. Pharm. (Dibrugarh University)
  2. Master’s Degree: M. Pharm. (Birla Institute of Technology, Mesra)
  3. Ph.D.: Ph. D (Pharmacy) (Jadavpur University, Kolkata)
  4. Other: PDCR (Catalyst Clinical Services, Delhi)

Professional Experience:     

  • 28+ Years (Teaching)

Areas of Interest/ Specialization:

  • Medicinal Chemistry/ Pharmaceutical Chemistry

Research Projects:                

Projects completed as PI:

  1. Project Title: Pharmacognostical and phytochemical study on Caesalpinia crista Linn, a herbal drug having folklore use in the treatment of malaria in Assam.
    Funding Agency (Scheme): AICTE (RPS)
    Amount: 8.7 Lakh
    Duration: 2006 - 2009
  2. Project Title: Phytochemical investigation and biological evaluation of active principles of the fruits of Garcinia cowa, an indigenous plant of Assam having folklore in the treatment of intestinalprotozoal infection
    Funding Agency (Scheme): UGC (Minor Research Project)
    Amount: 1.0 Lakh
    Duration: 2006 - 2008
  3. Project Title: Phytochemical investigation and Biological evaluation of Sarcochlamys pulcherrima, an indigenous plant of ethnomedicinal importance in Missing community of Assam
    Funding Agency (Scheme): UGC (Minor Research Project)
    Amount: 1.395 Lakh
    Duration: 2011 - 2013

Other Projects:

A.  Projects completed as Chief Coordinator:

  1. Project Title: Upgradation of laboratory facility for antimalarial activity screening
    Funding Agency (Scheme): AICTE (MODROBS)
    Amount: 12.72 Lakh
    Duration: 2012 - 2013

B.  Projects ongoing as Coordinator:

  1. Project Title: Antimalarial drug discovery from natural sources/by chemical synthesis from available lead molecules/through repositioning
    Funding Agency (Scheme): UGC (UGC-SAP, DRS-I)
    Amount: 64.25 Lakhs
    Duration: 2016 - 2021

Ph.D Scholars:

 

Sl. No.

Name

Topic

Status (On-going/Completed)

01

Md. Kamaruz Zaman

Pharmacognostical and Phytochemical Investi -gations of some Antimal-arial Herbal Drugs of North-East India

Completed (Degree Awarded, 2010)

02

Anil Kumar Saikia

Studies on Chemical Composition and Biological Activities of Essential oils of Medicinal and Aromatic plants grown in North East India

Completed (Degree Awarded, 2011)

03

Aparoop Das

Isolation, Characterization and preparation of Semi-synthetic Derivatives of the Active principles of Garcinia cowa Roxb. and their Biological Evaluation

Completed (Degree Awarded, 2012)

04

Lalzikpuii

Isolation, Characterization and Biological Evaluation of Active principles of Aporusa oblonga

Completed (Degree Awarded, 2013)

05

Bhupendra Singh

Synthesis of some novel 4-Aminoquinoline Mannich bases and Evaluation for Antimalarial activity

Completed (Degree Awarded, 2014)

06

Antesh Jha

Design and Development of Fast Dissolving Drug Delivery Tablets of Glipizide by using Starch and Natural Super Disintegrants

Completed (Degree Awarded, 2015)

07

Bikash Ch. Deb

Pharmacognostical Characterisation and Biological Evaluation of Sarcochlamys pulcherrima

Completed (Degree Awarded, 2015)

08

Atul Kumar

Studies on Production of 6-Aminopenicillanic acid by using Locally Isolated Different Free and Immobilized Soil Microbes

Completed (Degree Awarded, 2015)

09

Mukesh Kr. Kumawat

Synthesis and Antimalarial activity Evaluation of some Novel Tetraoxane Derivatives

Completed (Degree Awarded, 2016)

10

Kh. Deepak Singh

Evaluation of Biological Activities of Allium hookerii Thw. Enum.

Completed (Degree Awarded, 2016)

11

Biman Bhuyan

Phytochemical and Biological Evaluation of some Costus species of Assam

Thesis submitted

12

Mithun Rudrapal

Design, Synthesis and Evaluation of 1, 2, 4-Trioxane Derivatives for Antimalarial activity

Completed (Degree Awarded, 2018)

13

Chandrajit Dohutia

Design, Synthesis and Evaluation of Curcumin derivatives for Antimalarial Activity

Thesis submitted

14

Partha Pratim Kaishap

(Jt. Guidance with

Dr. S. Gogoi, CSIR-NEIST, Jorhat)

Synthesis and biological evaluation of a series of new aza-heterocyclic compounds for anti-inflammatory and cytotoxic activities

Completed (Degree Awarded, 2018)

15

Neelutpal Gogoi

Identification of Antimalarial

Phytoconstituents in some selected

Traditional Herbal Remedies of Assam

On-going

 

Administrative Assignments

  • Head, Dept. of Pharm. Sciences, Dibrugarh University
  • Dean, Research & Development, Dibrugarh University

Extension Service:

  • Professional activities

Publications

Publications:

Papers published in Journals:

  1. Extraction, Purification and Physico-chemical Properties of a Proteolytic Enzyme from the Latex of Ficus hispida Linn., Chetia D., Nath L. K., Dutta S. K.,  Indian J. Pharm. Sci, 1999, 61(1), 29-33, IF: 0.762, ISSN: 1998-3743
  2. Purification and characterization of a Protease from Ficus hispida Linn., Chetia D., Nath L. K., Dutta S. K., Indian J. Pharm. Sci,  2001,63(2), 132-136, IF: 0.762, ISSN: 1998-3743
  3. Pharmacological Properties of a Protease from Ficus hispida Linn., Chetia D., Nath L. K., Dutta S. K., Ancient Science of Life, 2001, Vol XXI(2), 99-110
  4. Pharmacognostic studies of the trunk bark of Machilus bombycina (Persia bombycina) King ex Hook. f., Chetia D., Zaman K., Bull. Life Sci., 2008, Vol- XIV, 1-10, ISSN: 0971-5746
  5. Essential oil composition of leaves and fruits of Litsea cubeba Pers. grown in upper Assam region of India, Zaman K., Chetia D., Saikia A.K., Ali M., Bull. Life Sci., 2008, Vol-XIV, 20-25, ISSN: 0971-5746
  6. Synthesis and Evaluation of 7-Chloro-4-Aminoquinoline Mannich base Derivatives for Antimalarial Activity, Singh B., Kumawat M.K., Chetia D., Bull. Life Sci, 2008, Vol. XIV, 11-19, ISSN: 0971-5746
  7. Synthesis and Antimalarial Screening of Some New Isoquine Analogues, Saha C., Bhattacharya S., Chetia D., Int. J. ChemTech Res., 2009, 1(2), 322-328, ISSN: 0974-4290
  8. Study on the Pattern of Drug Usage in Urban Areas of Nagaland, Longchar S., Bora S., Chetia D., Bull. Life Sci, 2009, Vol. XV, 77-82, ISSN: 0971-5746
  9. Synthesis and Evaluation of Some New Isoquine Analogues for Antimalarial Activity, Saha C., Bhattacharya S., Chetia D, E-Journal of Chemistry, 2009, 6(S), S381-S389, IF: 0.77 ISSN: 0973-4945
  10. Synthesis and antimalarial activity evaluation of some new 7-chloro-4-aminoquinolines with substituted ring at side chain, Rudrapal M, Chetia D., Prakash A, Der Pharma Chemica, 2010, 2(1): 194-203, ISSN: 0975-413X
  11. Synthesis and antibacterial activity evaluation of some novel 7-chloro-4-aminoquinoline derivatives, Rudrapal M, Chetia D., Int. Journal of ChemTech Research,2010, 2 (3), 1606-1611, ISSN: 0974-4290
  12. Synthesis and Antibacterial Activity of Some 2,4,6-trisubstituted-1,3,5-triazines, Singh UP, Das A, Chetia D., Bhattacharya A, Subhasch YP, Kumar V, Bhatt HR, Lat. Am. J. Pharm., 2010, 29 (4), 607-11, IF: 0.372, ISSN: 0326-2383
  13. Synthesis and antibacterial Activity Screening of some 4-aminoquinolines with substituted ring at side chain, Rudrapal M, Chetia D., Indian J Pharm Sciences, 2010, 72 (2), 278, IF: 0.762, ISSN: 0250-474X
  14. Synthesis and in vitro and in vivo antimalarial activity of novel 4-anilinoquinoline Mannich base derivatives, Singh B, Chetia D., Puri SK, Srivastava K, Prakash A, Med Chem Res, 2011, 20:1523–1529, IF:1.436, ISSN: 1054-2523 (Print) 1554-8120 (Online)
  15. Synthesis and antimalarial activity evaluation of some isoquine analogues, Bora S, Chetia D., Prakash A, Med Chem Res, 2011, 20 (9), 1632-1637, IF:1.436, ISSN: 1054-2523 (Print) 1554-8120 (Online)
  16. Study on the Use of Medicines in some Selected Healthcare Facilities of Arunachal Pradesh, Chetia D., Nada N, Rudrapal M, Asian J  Pharm Clin Res, 2011, 4(3), 80-81, ISSN: 0974-2441
  17. Development and Statistical Analysis of Glipizide-loaded Fast-dissolving Tablets Using Plantago ovata Husk as a Superdisintegrant, Jha A K, Chetia D., International Journal of Pharmaceutical Compounding, 2011, 15(6), 521-525
  18. Novel 4-aminoquinoline analogues as antimalarial agents: A review, Rudrapal M, Chetia D., Der Pharmacia Lettre, 2011, 3(3): 29-36, ISSN: 0975-5071
  19. Formulation and evaluation of glipizide-loaded Fast-Dissolving Tablets using husk of Plantugo ovata as a superdisintegrant, Jha AK, Chetia D., Asian Journal of Pharmaceutics, Oct-Dec 2011, 198-202, ISSN: 0973-8398 (Print), 1998-409X (Online)
  20. Development of natural gum based fast disintegrating tablets of glipizide, Jha A K, Chetia D., Asian Journal of Pharmaceutics, Oct-Dec 2012, 282-288, ISSN: Print-0973-8398, Online- 1998-409X
  21. Study on the Ethnomedicinal System of Manipur, Rajesh Singh Y, Ch. Onita Devi, S. Kr. Singh A., Chetia D., International Journal of Pharmaceutical & Biological Archives, 3(3), 2012, 507-511, ISSN: 0976-3333
  22. Studies on Antiinflammatory, Antipyretic and Analgesic Activities of Aporusa oblonga Mull Arg, Sailo Lalzikpuii, Sailo L., Chetia D., Asian J. Chem., 24 (11), 2012, 4995-4999, IF: 0.355, ISSN: 0975-427X (Online), ISSN: 0970-7077 (Print)
  23. Synthesis and study of analgesic, anti-inflammatory activities of bis (indolyl) methanes (BIMS), Kaishap P P, Dohutia C, Chetia D., IJPSR, 2012; Vol. 3(11): 1000-1006, ISSN: 0975-8232
  24. Synthesis and in-vitro Antimalarial Activity of Some New 4-Amino quinoline Mannich Base Derivatives, Roy S, Chetia D., Rudrapal M, Prakash A, International Journal of Drug Design and Discovery, 2012, 3 (2), 803-808
  25. Phytochemical Screening and Gut Motility Activity of Pongamia pinnata Bark in Experimental Animal Models, Singh K D, Chetia D., Int J Pharm Bio Sci, Jan 4(1), 2013, 63-69, IF: 0.47, ISSN: 0975-6299
  26. Synthesis and Study of Analgesic, Anti-inflammatory Activities of 3-Methyl-5-pyrazolone Derivatives, Dohutia C, Kaishap PP, Chetia D., Int J Pharm Pharm Sci, 2013, Vol 5, Issue 1, 86-90
  27. Screening of fruit and leaf essential oils of Litsea cubeba Pers. from north-east India – chemical composition and antimicrobial activity, Saikia AK, Chetia D., D’Arrigob M, Smeriglio A, Strano T, Ruberto G, The Journal of Essential Oil Research, 2013, 1-9, IF: 0.871 ISSN: 1041-2905 (Print), 2163-8152 (Online)
  28. In-silico docking studies of selected n-glycoside bearing tetrazole ring in the treatment of hyperglycemia showing inhibitory activity on SGLT, Kumari B, Chetia D., Int J Pharm Pharm Sci, 2013,Vol 5, Suppl 2, 633-638, ISSN: 0975-1491
  29. Synthesis and Antimalarial Activity Study of Some New Mannich Bases of 7-Chloro-4-Aminoquinoline, Roy S, Chetia D., Rudrapal M, Prakash A, Medicinal Chemistry, 2013, 9, 379-383, IF:1.458, ISSN: 1573-4064
  30. Docking studies on quinine analogs for Plasmepsin-II of malaria parasite using Bioinformatics tools, Sharma RB, Chetia D., Int J Pharm Pharm Sci, 2013,Vol 5, Suppl 3, 681-685, ISSN: 0975-1491
  31. Pharmacophore Mapping, Three Dimensional QSAR Analysis and Docking Study of Quinoline Derivatives as Potent Plasmepsin Inhibitors, Sharma R B, Deka R C, Sharma HK, Chetia D, International Journal of Recent Scientific Research, 2013, vol. 4, Issue 11, 1871-1874, ISSN: 0976-3031
  32. Preliminary Phytochemical Investigation on Rhizomes of Costus speciosus found in Assam, India, Bhuyan B, Chetia D, Rajak P, PHARMANEST, Vol. 4, Issue 6, 2013, 1447-1457, ISSN: 2231-0541
  33. Antidiabetic activity of methnolic extract of Allium hookerii leaves, Singh KD, Chetia D, Mazumdar S, Indo American Journal of Pharm Research, 2013, Vol. 3, Issue 6, 4098-4104, ISSN: 2231-6876
  34. Synthesis, antimalarial-, and antibacterial activity evaluation of some new 4-aminoquinoline derivatives, Rudrapal M, Chetia D, Prakash A, Med Chem Res, 2013, 22, 3703–3711, IF: 1.436, ISSN: 1054-2523 (Print) 1554-8120 (Online)
  35. In vitro-in vivo performance evaluation of treated Plantago ovata husk based fast dissolving tablets of glipizide: Flashtab technology, Jha AK, Chetia D, Asian J Pharm, 2014; 8: 250-8, ISSN: Print -0973-8398, Online - 1998-409X
  36. Pharmacognostical studies on the leaves of Sarcochlamys pulcherrima (Roxb) Goud., Deb BC, Kumar A, Chetia D, Indian Journal of Natural Products and Resources, 2014, 5 (2), 164-170
  37. Antiulcer and in vitro antioxidant activity of Allium hookerii: an ethnomedicinal plant of Manipur, Singh K D, Chetia D, Junejo JA, Asian J Pharm Clin Res, Vol 8, Issue 5, 2015, 130-135, ISSN: 0974-2441
  38. Molecular docking studies of some novel 1,2,4,5-tetraoxane derivatives as antimalarial agents, Kumawat MK, Chetia D, World Journal of Pharmacy and Pharmaceutical Sciences, Vol 4, Issue 10, 2015, ISSN: 2278 – 4357
  39. Synthesis, antimalarial activity evaluation and molecular docking studies of some novel dispiro-1,2,4,5-tetraoxanes, Kumawat M. K., Chetia D., Bangladesh J Pharmacol, 2015, 10, 917-923, IF: 0.671, ISSN: 1991-0088
  40. Design, Synthesis and Antimalarial Activity of Some New 2-Hydroxy-1,4-naphthoquinone-4-hydroxyaniline Hybrid Mannich Bases, Sharma D, Chetia D, Rudrapal M,  Asian J. Chem., 28 (4), 782-788, 2016, IF: 0.355, ISSN: 0975-427X (Online), 0970-7077 (Print)
  41. Synthesis, antimalarial activity evaluation and docking studies of some novel tetraoxaquines, Kumawat M. K., Chetia D., Parida P., Med Chem Res, 2016, DOI 10.1007/s00044-016-1644-5. IF: 1.436, ISSN: 1054-2523 (Print) 1554-8120 (Online)
  42. Molecular docking studies of some novel hybrid tetraoxaquines & dispirotetraoxanes as antimalarial agents, Kumawat M. K., Chetia D., Int J Pharm Sci Res, 2016, 7(3), 1348-1359. E-ISSN: 0975-8232; P-ISSN: 2320-5148
  43. Synthesis and evaluation of hybrid Mannich base-tetraoxane derivatives as potent anti-malarial agents, Sarma M., Chetia D., Singh, K. D., Banu Z. W., Dohutia C., 2016, Int J Pharm Anal Res, 2016, 5(2), 287-293. ISSN: 2320-2831
  44. QSAR Analysis of 7-Chloro-4-Aminoquinoline Derivatives as Antimalarial Agents, Rudrapal M., Chetia D., Asian J Org Med Chem, 2016, 1(2), 51-54
  45. Synthesis and Antimalarial Activity Evaluation of 3-(3-(7-chloroquinolin-4-ylamino)propyl)-1,3-thiazinan-4-one Derivatives, Kumawat M K, Singh U P, Singh B, Prakash A, Chetia D, Arabian Journal of Chemistry, 2016, 9, S643-S647, IF: 3.613,  ISSN: 1878-5352
  46. Synthesis and Antimalarial Activity Evaluation of Some Mannich Bases of Tetraoxane-Phenol Conjugate, Gogoi J, Chetia D, Kumawat MK, Rudrapal M, Indian Journal of Pharmaceutical Education and Research, 50, 4,  Oct-Dec, 2016, 591-597, IF: 0.219, ISSN: 0019-5464
  47. Endoperoxide antimalarials: development, structural diversity and pharmacodynamic aspects with reference to 1,2,4-trioxane-based structural scaffold, Rudrapal M, Chetia D, Drug Design, Development and Therapy, 2016:10 3575–3590, IF: 2.962,  ISSN: 1177-8881
  48. Curcumin Against Malaria: From Traditional Medicine to Development of Synthetic Analogs; A Bioorganic Approach, Dohutia C, Chetia D, Singh KD, Current Traditional Medicine, 2016, 2(2), 124-133, ISSN: 2215-0846 (Online), 2215-0838 (Print)
  49. In vitro evaluation of the antimalarial activity of a designed novel quinuclidine derivative, Sharma R, Goswami A, Rudrapal M, Sharma D, Sharma HK, Chetia D, Current Science, 2016, 111(12), 2028-2030, IF: 0.967, ISSN: 0011-3891
  50. Synthesis, Antimalarial Activity Evaluation and Drug-likeness Study of Some New Quinoline-Lawsone Hybrids, Kashyap A, Chetia D, Rudrapal M, Indian J Pharm Science, 2016, 78 (6), 892-911, IF: 0.762, ISSN: 0250-474X
  51. Ethno-medicinal Survey on Tai-Ahom Community of Assam,  Dohutia C,  Chetia D, Upadhyaya S, Ethno Med, 2016, 10(4): 461-471
  52. QSAR Study of Trioxane Derivatives as Antimalarial Agents, Rudrapal M, Chetia D, Current Trends in Pharmaceutical Research, 2016, 3(1), 1-17, ISSN: 2310-4820
  53. GA3 Assisted Seed Dormancy Breaking in Abelmoschus mochatus Medic. Subsp. Mochatus, Gogoi G, Borua PK, Chetia D, Cercetari Agronomice in Moldova, 2016, XLIX, 4 (168), 27-34, ISSN: 0379-5837 (Print),   2067-1865 (Electronic), www.uaiasi.ro/CERCET_AGROMOLD
  54. Isolation of Two New Cheilanthane-Type Tricarboxylic Sesterterpenoids from Leaves of Caesalpinia crista Linn.: A Traditionally Used Plant of Assam, India, Zaman K, Chetia D, Ali M, Asian J. Chem., 2017, 29 (3), 485-488, IF: 0.355, ISSN: 0975-427X (Online), 0970-7077 (Print)
  55. Ru(II)-Catalyzed annulation of benzamidines and alkynes by C–H/ N–H activation: a facile synthesis of 1-aminoisoquinolines, Kaishap PP, Duarah G, Chetia D, Gogoi S,  Org. Biol. Chem., 2017, 15,  3491-3498, IF: 3.559, Rsc.li/obc (Royal Society of Chemistry)
  56. Design, in silico  and in vitro  evaluation  of curcumin analogues against Plasmodium falciparum, Dohutia C, Chetia D, Gogoi K, Sarma K, Experimental Parasitology, 2017, 175, 51–58, IF: 1.724
  57. Novel series of 1,2,4-trioxane derivatives as antimalarial agents, Rudrapal M, Chetia D, Singh V, Journal of Enzyme Inhibition and Medicinal Chemistry, 2017, 32 (1), 1159–1173, IF: 4.293, ISSN: 1475-6366 (Print) , 1475-6374 (Online)
  58. Molecular docking, synthesis and in vitro antimalarial evaluation of certain novel curcumin analogues, Dohutia C, Chetia D, Gogoi K, Bhattacharyya DR, Sarma K, Braz. J. Pharm. Sci., 2017, 53 (4), IF: 0.474, 1-14: e00084
  59. Plant flavonoids as potential source of future antimalarial leads, Rudrapal M, Chetia D, Systematic Reviews in Pharmacy, 2017, 8 (1), 13
  60. Ruthenium(II)-Catalyzed Synthesis of Spirobenzofuranones by a Decarbonylative Annulation Reaction, Kaishap PP, Duarah G, Sarma B, Chetia D, Gogoi S, Angew. Chem. Int. Ed.,  2018, 57,   456 –460, IF: 11.994,  www.angewandte.org
  61. Newer series of trioxane derivatives as potent antimalarial agents, Rudrapal M, Banu Z W,   Chetia D, Med Chem Res, 2018, 27:653–668, IF:1.436,  www.link.springer.com/journal
  62. Synthesis and Antimalarial Activity of Lawsone Mannich Base Derivatives, Medhi A, Chetia D,  Rudrapal M, Indian Journal of Pharmaceutical Education and Research,  2018, 52 (3), Jul-Sep, 472-479, IF: 0.219, www.ijper.org
  63. An ethnomedicinal study focusing the genus Costus in Assam with emphasis on traditional medicine, Bhuyan B, Chetia D, Journal of Medicinal Plants, 6 (2), 178-188

Books and Book Chapters:

Books Published/Edited:

  1. Management of Natural Resources for Better Health Care (Proceedings of National Seminar, Dept. of Pharm. Sciences, Dibrugarh University), Dolui A. K.(Ed), Das S., Chetia D. (Associate Editors), Registrar, Dibrugarh University, 2002, ISBN: 81-88424-00-5
  2. Novel Antimalarial Drugs: Study of Amino-quinoline Mannich Bases, Singh B, Chetia D, LAP LAMBERT Academic Publishing, Germany, 2012, ISBN: 978-3-659-25371-3
  3. Malaria: Chemotherapy and Development of Novel Antimalarial Agents, Rudrapal M, Chetia D, LAP LAMBERT Academic Publishing, Germany, 2013, ISBN: 978-3-659-11756-5
  4.  Costus Speciosus: A Complete Study as Hepatoprotectant, Bhuyan B, Chetia D, LAP LAMBERT Academic Publishing, Germany, 2014, ISBN-10: 3659495239, ISBN-13: 9783659495236
  5. Development of some novel Antimalarial agents, Kumawat MK, Chetia D, LAP LAMBERT Academic Publishing, Germany, 2017, ISBN: 978-3-330-05284-0

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